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10.1097/MOU.0000000000000316 http://scihub22266oqcxt.onion/10.1097/MOU.0000000000000316 C5035435!5035435!27262138     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27262138&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Urol 2016 ; 26 (5): 459-65 Nephropedia Template TP {{tp|p=27262138|t=2016. Beyond PSA: Utilizing Novel Strategies to Screen Men for Prostate Cancer |pdf=|usr=}}{{27262138}} gab.com Text Beyond PSA: Utilizing Novel Strategies to Screen Men for Prostate Cancer JO: Curr Opin Urol http://www.kidney.de/pget.php?&tw=1&pmid=27262138 #FOAvip Purpose of Review: The purpose of this article is to review blood and urine tests that are currently available and under investigation for a role in prostate cancer screening and detection. Recent Findings: Compared to total PSA alone, its combination with percent free-to-total PSA contributes greater specificity for prostate cancer, and is a component of 2 newer blood tests called the 4kScore and Prostate Health Index. All three tests improve the prediction of high-grade disease and are commercially available options to aid in initial or repeat prostate biopsy decisions. PCA3 is a urinary marker that is currently available for repeat prostate biopsy decisions. Although PCA3 alone has inferior prediction of clinically significant disease and requires collection of urine after digital rectal examination, it may be combined with other clinical variables or other urine markers like TMPRSS2:ERG to improve performance. Little data is available to support a role for single nucleotide polymorphisms or other investigational markers in early detection. Summary: Several commercially available blood and urine tests have to been shown to improve specificity of PSA for high-grade prostate cancer. Use of such tests would decrease unnecessary biopsy and overdiagnosis of indolent disease. Biopsy of men with moderately elevated PSA without use of such a reflex test should be discouraged. Twit Text FOAVip Beyond PSA: Utilizing Novel Strategies to Screen Men for Prostate Cancer ????Curr Opin Urol http://www.kidney.de/pget.php?&tw=1&pmid=27262138 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27262138 #FOAvip English Wikipedia <ref>{{Cite pmid|27262138}}</ref> Beyond PSA: Utilizing Novel Strategies to Screen Men for Prostate Cancer #MMPMID27262138 Loeb S; Lilja H; Vickers A Curr Opin Urol 2016[Sep]; 26 (5): 459-65 PMID27262138show ga Purpose of Review: The purpose of this article is to review blood and urine tests that are currently available and under investigation for a role in prostate cancer screening and detection. Recent Findings: Compared to total PSA alone, its combination with percent free-to-total PSA contributes greater specificity for prostate cancer, and is a component of 2 newer blood tests called the 4kScore and Prostate Health Index. All three tests improve the prediction of high-grade disease and are commercially available options to aid in initial or repeat prostate biopsy decisions. PCA3 is a urinary marker that is currently available for repeat prostate biopsy decisions. Although PCA3 alone has inferior prediction of clinically significant disease and requires collection of urine after digital rectal examination, it may be combined with other clinical variables or other urine markers like TMPRSS2:ERG to improve performance. Little data is available to support a role for single nucleotide polymorphisms or other investigational markers in early detection. Summary: Several commercially available blood and urine tests have to been shown to improve specificity of PSA for high-grade prostate cancer. Use of such tests would decrease unnecessary biopsy and overdiagnosis of indolent disease. Biopsy of men with moderately elevated PSA without use of such a reflex test should be discouraged. äBeyond PSA: Utilizing Novel Strategies to Screen Men for Prostate Canc(epmc).pdf DeepDyve Pubget Overpricing