Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1158/1078-0432.CCR-14-2921 http://scihub22266oqcxt.onion/10.1158/1078-0432.CCR-14-2921 C5034890!5034890!25573382     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Cancer+Res 2015 ; 21 (5): 969-75 Nephropedia Template TP {{tp|p=25573382|t=2015. Zebrafish: a new companion for translational research in oncology |pdf=|usr=}}{{25573382}} gab.com Text Zebrafish: a new companion for translational research in oncology JO: Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=25573382 #FOAvip In an era of high-throughput ?omic? technologies, the unprecedented amount of data that can be generated presents a significant opportunity but simultaneously an even greater challenge for oncologists trying to provide personalized treatment. Classically, pre-clinical testing of new targets and identification of active compounds against those targets has entailed the extensive use of established human cell lines, as well as genetically modified mouse tumor models. Patient-derived xenografts in zebrafish may in the near future provide a platform for selecting an appropriate personalized therapy and together with zebrafish transgenic tumor models represent an alternative vehicle for drug development. The zebrafish is readily genetically modified. The transparency of zebrafish embryos and the recent development of pigment deficient zebrafish afford researchers the valuable capacity to observe directly cancer formation and progression in a live vertebrate host. The zebrafish is amenable to transplantation assays that test the serial passage of fluorescently labelled tumor cells as well as their capacity to disseminate and/or metastasize. Progress achieved to date in genetic engineering and xenotransplantation will establish the zebrafish as one of the most versatile animal models for cancer research. A model organism that can be used in transgenesis, transplantation assays, single cell functional assays and in vivo imaging studies make zebrafish a natural companion for mice in translational oncology research. Twit Text FOAVip Zebrafish: a new companion for translational research in oncology ????Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=25573382 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25573382 #FOAvip English Wikipedia <ref>{{Cite pmid|25573382}}</ref> Zebrafish: a new companion for translational research in oncology #MMPMID25573382 Barriuso J; Nagaraju R; Hurlstone A Clin Cancer Res 2015[Mar]; 21 (5): 969-75 PMID25573382show ga In an era of high-throughput ?omic? technologies, the unprecedented amount of data that can be generated presents a significant opportunity but simultaneously an even greater challenge for oncologists trying to provide personalized treatment. Classically, pre-clinical testing of new targets and identification of active compounds against those targets has entailed the extensive use of established human cell lines, as well as genetically modified mouse tumor models. Patient-derived xenografts in zebrafish may in the near future provide a platform for selecting an appropriate personalized therapy and together with zebrafish transgenic tumor models represent an alternative vehicle for drug development. The zebrafish is readily genetically modified. The transparency of zebrafish embryos and the recent development of pigment deficient zebrafish afford researchers the valuable capacity to observe directly cancer formation and progression in a live vertebrate host. The zebrafish is amenable to transplantation assays that test the serial passage of fluorescently labelled tumor cells as well as their capacity to disseminate and/or metastasize. Progress achieved to date in genetic engineering and xenotransplantation will establish the zebrafish as one of the most versatile animal models for cancer research. A model organism that can be used in transgenesis, transplantation assays, single cell functional assays and in vivo imaging studies make zebrafish a natural companion for mice in translational oncology research. äZebrafish: a new companion for translational research in oncology (epmc).pdf DeepDyve Pubget Overpricing