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10.1016/j.jaci.2016.02.004 http://scihub22266oqcxt.onion/10.1016/j.jaci.2016.02.004 C5030841!5030841!27059726     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Allergy+Clin+Immunol 2016 ; 137 (4): 984-97 Nephropedia Template TP {{tp|p=27059726|t=2016. Molecular and Cellular Mechanisms of Food Allergy and Food Tolerance |pdf=|usr=}}{{27059726}} gab.com Text Molecular and Cellular Mechanisms of Food Allergy and Food Tolerance JO: J Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=27059726 #FOAvip Ingestion of innocuous antigens, including food proteins, normally results in local and systemic immune nonresponsiveness in a process termed oral tolerance. Oral tolerance to food proteins is likely to be intimately linked to mechanisms that are responsible for gastrointestinal tolerance to large numbers of commensal microbes. Here, we review our current understanding of the immune mechanisms responsible for oral tolerance and how perturbations in these mechanisms may promote the loss of oral tolerance and development of food allergies. Roles for the commensal microbiome in promoting oral tolerance, and the association of intestinal dysbiosis with food allergy, are discussed. Growing evidence supports cutaneous sensitization to food antigens as one possible mechanism leading to the failure to develop or loss of oral tolerance. A goal of immunotherapy for food allergies is to induce sustained desensitization, or even true long-term oral tolerance, to food allergens through mechanisms that may in part overlap with those associated with the development of natural oral tolerance. Twit Text FOAVip Molecular and Cellular Mechanisms of Food Allergy and Food Tolerance ????J Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=27059726 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27059726 #FOAvip English Wikipedia <ref>{{Cite pmid|27059726}}</ref> Molecular and Cellular Mechanisms of Food Allergy and Food Tolerance #MMPMID27059726 Chinthrajah RS; Hernandez JD; Boyd SD; Galli SJ; Nadeau KC J Allergy Clin Immunol 2016[Apr]; 137 (4): 984-97 PMID27059726show ga Ingestion of innocuous antigens, including food proteins, normally results in local and systemic immune nonresponsiveness in a process termed oral tolerance. Oral tolerance to food proteins is likely to be intimately linked to mechanisms that are responsible for gastrointestinal tolerance to large numbers of commensal microbes. Here, we review our current understanding of the immune mechanisms responsible for oral tolerance and how perturbations in these mechanisms may promote the loss of oral tolerance and development of food allergies. Roles for the commensal microbiome in promoting oral tolerance, and the association of intestinal dysbiosis with food allergy, are discussed. Growing evidence supports cutaneous sensitization to food antigens as one possible mechanism leading to the failure to develop or loss of oral tolerance. A goal of immunotherapy for food allergies is to induce sustained desensitization, or even true long-term oral tolerance, to food allergens through mechanisms that may in part overlap with those associated with the development of natural oral tolerance. äMolecular and Cellular Mechanisms of Food Allergy and Food Tolerance (epmc).pdf DeepDyve Pubget Overpricing