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2016 ; 5
(1
): 1605
Nephropedia Template TP
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English Wikipedia
Decompressive craniectomy for severe traumatic brain injury: clinical study,
literature review and meta-analysis
#MMPMID27652178
Springerplus
2016[]; 5
(1
): 1605
PMID27652178
show ga
OBJECTIVE: To examine the clinical and neurological outcome of patients who
sustained a severe non-penetrating traumatic brain injury (TBI) and underwent
unilateral decompressive craniectomy (DC) for refractory intracranial
hypertension. DESIGN: Single center, retrospective, observational. SETTING: Level
I Trauma Center in Portland, Maine. PATIENTS: 31 patients aged 16-72 of either
sex who sustained a severe, non-penetrating TBI and underwent a unilateral DC for
evacuation of parenchymal or extra-axial hematoma or for failure of medical
therapy to control intracranial pressure (ICP). INTERVENTIONS: Review of the
electronic medical record of patients undergoing DC for severe TBI and assessment
of extended Glasgow Outcome Score (e-GOS) at 6-months following DC. MEASUREMENTS
AND MAIN RESULTS: The mean age was 39.3y ± 14.5. The initial GCS was 5.8 ± 3.2,
and the ISS was 29.7 ± 6.3. Twenty-two patients underwent DC within the first
24 h, two within the next 24 h and seven between the 3rd and 7th day post injury.
The pre-DC ICP was 30.7 ± 10.3 and the ICP was 12.1 ± 6.2 post-DC. Cranioplasty
was performed in all surviving patients 1-4 months post-DC. Of the 29 survivors
following DC, the e-GOS was 8 in seven patients, and 7 in ten patients. The e-GOS
was 5-6 in 6 others. Of the 6 survivors with poor outcomes (e-GOS = 2-4), five
were the initial patients in the series. CONCLUSIONS: In patients with
intractable cerebral hypertension following TBI, unilateral DC in concert with
practice guideline directed brain resuscitation is associated with good
functional outcome and acceptable-mortality.