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10.1017/S1551929516000018

http://scihub22266oqcxt.onion/10.1017/S1551929516000018
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C5028133!5028133!27660591
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suck abstract from ncbi


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pmid27660591      Micros+Today 2016 ; 24 (2): 24-31
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  • Secondary Ion Mass Spectrometry Imaging of Tissues, Cells, and Microbial Systems #MMPMID27660591
  • Gamble LJ; Anderton CR
  • Micros Today 2016[Mar]; 24 (2): 24-31 PMID27660591show ga
  • Secondary ion mass spectrometry (SIMS) is a technique capable of imaging tissues, single cells, and microbes revealing chemical species with sub-micrometer spatial resolution. The recently developed Fourier transform ion cyclotron resonance (FTICR) SIMS instrument provides high mass resolving power and mass accuracy, ToF-SIMS can generate chemical maps with an order of magnitude better lateral resolution than the FTICR-SIMS, and the NanoSIMS instrument offers sub-100 nm spatial resolution in chemical imaging. Many commercial ToF-SIMS instruments are also capable of depth profiling that allows three-dimensional reconstructions of cell and tissue structure.
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