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10.1111/xen.12235 http://scihub22266oqcxt.onion/10.1111/xen.12235 C5027196!5027196!27225644     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Xenotransplantation 2016 ; 23 (3): 211-21 Nephropedia Template TP {{tp|p=27225644|t=2016. Magneto-encapsulated human islets xenotransplanted into swine: A comparison of different transplantation sites |pdf=|usr=}}{{27225644}} gab.com Text Magneto-encapsulated human islets xenotransplanted into swine: A comparison of different transplantation sites JO: Xenotransplantation http://www.kidney.de/pget.php?&tw=1&pmid=27225644 #FOAvip Background: The fate of magnetically-labeled, barium-gelled Alginate/Protamine Sulfate/Alginate microcapsules (APSA magnetocapsules) following xenotransplantation was assessed by magnetic resonance imaging (MRI) and histopathology. Methods: Magnetocapsules with and without human islets were transplanted into 5 different clinically accessible sites of swine: portal vein, subcutaneous tissue, skeletal muscle, the liver and kidney subcapsular space. The surface of APSA magnetocapsules was modified using clinical grade heparin to mitigate an instant blood-mediated inflammatory reaction. Results: The accuracy of site-specific delivery was confirmed using a clinical 1.5T MRI setup, where the magnetocapsules appeared as distinct hypointense entities upon transplantation. As proven by the Lee While blood coagulation test, heparin-treated APSA magnetocapsules did not induce blood clotting for more than 48 hours in vitro. However, heparinized magnetocapsules induced innate and adaptive immune responses in vivo regardless of the transplantation site. Conclusions: We have demonstrated the feasibility of using a clinical 1.5T magnetic resonance imaging to non-invasively detect the accuracy of APSA magnetocapsule injection into various clinically accessible transplantation sites. Among the investigated transplantation sites, the liver and kidney subcapsular space were found to be the least immune-responsive towards xenografted encapsulated islets. Twit Text FOAVip Magneto-encapsulated human islets xenotransplanted into swine: A comparison of different transplantation sites ????Xenotransplantation http://www.kidney.de/pget.php?&tw=1&pmid=27225644 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27225644 #FOAvip English Wikipedia <ref>{{Cite pmid|27225644}}</ref> Magneto-encapsulated human islets xenotransplanted into swine: A comparison of different transplantation sites #MMPMID27225644 Arifin D; Valdeig S; Anders R; Bulte J; Weiss C Xenotransplantation 2016[May]; 23 (3): 211-21 PMID27225644show ga Background: The fate of magnetically-labeled, barium-gelled Alginate/Protamine Sulfate/Alginate microcapsules (APSA magnetocapsules) following xenotransplantation was assessed by magnetic resonance imaging (MRI) and histopathology. Methods: Magnetocapsules with and without human islets were transplanted into 5 different clinically accessible sites of swine: portal vein, subcutaneous tissue, skeletal muscle, the liver and kidney subcapsular space. The surface of APSA magnetocapsules was modified using clinical grade heparin to mitigate an instant blood-mediated inflammatory reaction. Results: The accuracy of site-specific delivery was confirmed using a clinical 1.5T MRI setup, where the magnetocapsules appeared as distinct hypointense entities upon transplantation. As proven by the Lee While blood coagulation test, heparin-treated APSA magnetocapsules did not induce blood clotting for more than 48 hours in vitro. However, heparinized magnetocapsules induced innate and adaptive immune responses in vivo regardless of the transplantation site. Conclusions: We have demonstrated the feasibility of using a clinical 1.5T magnetic resonance imaging to non-invasively detect the accuracy of APSA magnetocapsule injection into various clinically accessible transplantation sites. Among the investigated transplantation sites, the liver and kidney subcapsular space were found to be the least immune-responsive towards xenografted encapsulated islets. äMagneto-encapsulated human islets xenotransplanted into swine: A compa(epmc).pdf DeepDyve Pubget Overpricing