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2016 ; 17
(1
): 740
Nephropedia Template TP
gab.com Text
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Twit Text #
English Wikipedia
Allyl-isothiocyanate treatment induces a complex transcriptional reprogramming
including heat stress, oxidative stress and plant defence responses in
Arabidopsis thaliana
#MMPMID27639974
Kissen R
; Øverby A
; Winge P
; Bones AM
BMC Genomics
2016[Sep]; 17
(1
): 740
PMID27639974
show ga
BACKGROUND: Isothiocyanates (ITCs) are degradation products of the plant
secondary metabolites glucosinolates (GSLs) and are known to affect human health
as well as plant herbivores and pathogens. To investigate the processes engaged
in plants upon exposure to isothiocyanate we performed a genome scale
transcriptional profiling of Arabidopsis thaliana at different time points in
response to an exogenous treatment with allyl-isothiocyanate. RESULTS: The
treatment triggered a substantial response with the expression of 431 genes
affected (P < 0.05 and log2 ? 1 or ? -1) already after 30 min and that of 3915
genes affected after 9 h of exposure, most of the affected genes being
upregulated. These are involved in a considerable number of different biological
processes, some of which are described in detail: glucosinolate metabolism,
sulphate uptake and assimilation, heat stress response, oxidative stress
response, elicitor perception, plant defence and cell death mechanisms.
CONCLUSION: Exposure of Arabidopsis thaliana to vapours of allyl-isothiocyanate
triggered a rapid and substantial transcriptional response affecting numerous
biological processes. These include multiple stress stimuli such as heat stress
response and oxidative stress response, cell death and sulphur secondary defence
metabolism. Hence, effects of isothiocyanates on plants previously reported in
the literature were found to be regulated at the gene expression level. This
opens some avenues for further investigations to decipher the molecular
mechanisms underlying the effects of isothiocyanates on plants.