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10.1186/s13059-016-1055-4

http://scihub22266oqcxt.onion/10.1186/s13059-016-1055-4
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C5025577!5025577!27640875
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suck abstract from ncbi


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pmid27640875      Genome+Biol 2016 ; 17 (ä): ä
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  • DNA-guided genome editing using structure-guided endonucleases #MMPMID27640875
  • Varshney GK; Burgess SM
  • Genome Biol 2016[]; 17 (ä): ä PMID27640875show ga
  • The search for novel ways to target and alter the genomes of living organisms accelerated rapidly this decade with the discovery of CRISPR/Cas9. Since the initial discovery, efforts to find alternative methods for altering the genome have expanded. A new study presenting an alternative approach has been demonstrated that utilizes flap endonuclease 1 (FEN-1) fused to the Fok1 endonuclease, which shows potential for DNA-guided genome targeting in vivo.
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