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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Ann+Intensive+Care
2016 ; 6
(1
): 90
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Management of neutropenic patients in the intensive care unit (NEWBORNS EXCLUDED)
recommendations from an expert panel from the French Intensive Care Society
(SRLF) with the French Group for Pediatric Intensive Care Emergencies (GFRUP),
the French Society of Anesthesia and Intensive Care (SFAR), the French Society of
Hematology (SFH), the French Society for Hospital Hygiene (SF2H), and the French
Infectious Diseases Society (SPILF)
#MMPMID27638133
Schnell D
; Azoulay E
; Benoit D
; Clouzeau B
; Demaret P
; Ducassou S
; Frange P
; Lafaurie M
; Legrand M
; Meert AP
; Mokart D
; Naudin J
; Pene F
; Rabbat A
; Raffoux E
; Ribaud P
; Richard JC
; Vincent F
; Zahar JR
; Darmon M
Ann Intensive Care
2016[Dec]; 6
(1
): 90
PMID27638133
show ga
Neutropenia is defined by either an absolute or functional defect (acute myeloid
leukemia or myelodysplastic syndrome) of polymorphonuclear neutrophils and is
associated with high risk of specific complications that may require intensive
care unit (ICU) admission. Specificities in the management of critically ill
neutropenic patients prompted the establishment of guidelines dedicated to
intensivists. These recommendations were drawn up by a panel of experts brought
together by the French Intensive Care Society in collaboration with the French
Group for Pediatric Intensive Care Emergencies, the French Society of Anesthesia
and Intensive Care, the French Society of Hematology, the French Society for
Hospital Hygiene, and the French Infectious Diseases Society. Literature review
and formulation of recommendations were performed using the Grading of
Recommendations Assessment, Development and Evaluation system. Each
recommendation was then evaluated and rated by each expert using a methodology
derived from the RAND/UCLA Appropriateness Method. Six fields are covered by the
provided recommendations: (1) ICU admission and prognosis, (2) protective
isolation and prophylaxis, (3) management of acute respiratory failure, (4) organ
failure and organ support, (5) antibiotic management and source control, and (6)
hematological management. Most of the provided recommendations are obtained from
low levels of evidence, however, suggesting a need for additional studies. Seven
recommendations were, however, associated with high level of evidences and are
related to protective isolation, diagnostic workup of acute respiratory failure,
medical management, and timing surgery in patients with typhlitis.