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2016 ; 16
(3
): 263-9
Nephropedia Template TP
gab.com Text
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English Wikipedia
Mechanical Circulatory Support for the Failing Heart: Continuous-Flow Left
Ventricular Assist Devices
#MMPMID27660575
Englert JA 3rd
; Davis JA
; Krim SR
Ochsner J
2016[Fal]; 16
(3
): 263-9
PMID27660575
show ga
BACKGROUND: Heart transplantation remains the definitive therapy for patients
with advanced heart failure; however, owing to limited donor organ availability
and long wait times, continuous-flow left ventricular assist devices (LVADs) have
become standard therapy. METHODS: This review summarizes the history,
progression, function, and basic management of LVADs. Additionally, we provide
some clinical pearls and important caveats for managing this unique patient
population. RESULTS: Currently, the most common LVADs being implanted in the
United States are second- and third-generation devices, the HeartMate II
(Thoratec Corp., St. Jude Medical) and the HeartWare HVAD (HeartWare
International, Inc.). A newer third-generation pump, the HeartMate III (Thoratec
Corp., St. Jude Medical), is designed to create an artificial pulse and is
currently under investigation in the United States. CONCLUSION: LVAD use is
promising, will continue to grow, and has become standard therapy for advanced
heart failure as a bridge to recovery, as destination therapy, and as a bridge to
transplantation.