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10.1186/s12866-016-0833-1 http://scihub22266oqcxt.onion/10.1186/s12866-016-0833-1 C5024456!5024456!27629863     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Microbiol 2016 ; 16 (ä): ä Nephropedia Template TP {{tp|p=27629863|t=2016. Dental plaque bacteria with reduced susceptibility to chlorhexidine are multidrug resistant |pdf=|usr=}}{{27629863}} gab.com Text Dental plaque bacteria with reduced susceptibility to chlorhexidine are multidrug resistant JO: BMC Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=27629863 #FOAvip Background: Chlorhexidine (CHX) is used in oral care products to help control dental plaque. In this study dental plaque bacteria were grown on media containing 2 ?g/ml chlorhexidine gluconate to screen for bacteria with reduced CHX susceptibility. The isolates were characterized by 16S rRNA gene sequencing and antibiotic resistance profiles were determined using the disc diffusion method. Results: The isolates were variably resistant to multiple drugs including ampicillin, kanamycin, gentamicin and tetracycline. Two species, Chryseobacterium culicis and Chryseobacterium indologenes were able to grow planktonically and form biofilms in the presence of 32 ?g/ml CHX. In the CHX and multidrug resistant C. indologenes we demonstrated a 19-fold up-regulation of expression of the HlyD-like periplasmic adaptor protein of a tripartite efflux pump upon exposure to 16 ?g/ml CHX suggesting that multidrug resistance may be mediated by this system. Exposure of biofilms of these resistant species to undiluted commercial CHX mouthwash for intervals from 5 to 60 s indicated that the mouthwash was unlikely to eliminate them from dental plaque in vivo. Conclusions: The study highlights the requirement for increased vigilance of the presence of multidrug resistant bacteria in dental plaque and raises a potential risk of long-term use of oral care products containing antimicrobial agents for the control of dental plaque. Twit Text FOAVip Dental plaque bacteria with reduced susceptibility to chlorhexidine are multidrug resistant ????BMC Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=27629863 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27629863 #FOAvip English Wikipedia <ref>{{Cite pmid|27629863}}</ref> Dental plaque bacteria with reduced susceptibility to chlorhexidine are multidrug resistant #MMPMID27629863 Saleem HGM; Seers CA; Sabri AN; Reynolds EC BMC Microbiol 2016[]; 16 (ä): ä PMID27629863show ga Background: Chlorhexidine (CHX) is used in oral care products to help control dental plaque. In this study dental plaque bacteria were grown on media containing 2 ?g/ml chlorhexidine gluconate to screen for bacteria with reduced CHX susceptibility. The isolates were characterized by 16S rRNA gene sequencing and antibiotic resistance profiles were determined using the disc diffusion method. Results: The isolates were variably resistant to multiple drugs including ampicillin, kanamycin, gentamicin and tetracycline. Two species, Chryseobacterium culicis and Chryseobacterium indologenes were able to grow planktonically and form biofilms in the presence of 32 ?g/ml CHX. In the CHX and multidrug resistant C. indologenes we demonstrated a 19-fold up-regulation of expression of the HlyD-like periplasmic adaptor protein of a tripartite efflux pump upon exposure to 16 ?g/ml CHX suggesting that multidrug resistance may be mediated by this system. Exposure of biofilms of these resistant species to undiluted commercial CHX mouthwash for intervals from 5 to 60 s indicated that the mouthwash was unlikely to eliminate them from dental plaque in vivo. Conclusions: The study highlights the requirement for increased vigilance of the presence of multidrug resistant bacteria in dental plaque and raises a potential risk of long-term use of oral care products containing antimicrobial agents for the control of dental plaque. äDental plaque bacteria with reduced susceptibility to chlorhexidine ar(epmc).pdf DeepDyve Pubget Overpricing