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10.1111/ajt.13707 http://scihub22266oqcxt.onion/10.1111/ajt.13707 C5021128!5021128!26755448     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transplant 2016 ; 16 (7): 2139-47 Nephropedia Template TP {{tp|p=26755448|t=2016. Alloantibody Responses After Renal Transplant Failure Can Be Better Predicted by Donor?Recipient HLA Amino Acid Sequence and Physicochemical Disparities Than Conventional HLA Matching |pdf=|usr=}}{{26755448}} gab.com Text Alloantibody Responses After Renal Transplant Failure Can Be Better Predicted by Donor Recipient HLA Amino Acid Sequence and Physicochemical Disparities Than Conventional HLA Matching JO: Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=26755448 #FOAvip We have assessed whether HLA immunogenicity as defined by differences in donor?recipient HLA amino?acid sequence (amino?acid mismatch score, AMS; and eplet mismatch score, EpMS) and physicochemical properties (electrostatic mismatch score, EMS) enables prediction of allosensitization to HLA, and also prediction of the risk of an individual donor?recipient HLA mismatch to induce donor?specific antibody (DSA). HLA antibody screening was undertaken using single?antigen beads in 131 kidney transplant recipients returning to the transplant waiting list following first graft failure. The effect of AMS, EpMS, and EMS on the development of allosensitization (calculated reaction frequency [cRF]) and DSA was determined. Multivariate analyses, adjusting for time on the waiting list, maintenance on immunosuppression after transplant failure, and graft nephrectomy, showed that AMS (odds ratio [OR]: 1.44 per 10 units, 95% CI: 1.02?2.10, p = 0.04) and EMS (OR: 1.27 per 10 units, 95% CI: 1.02?1.62, p = 0.04) were independently associated with the risk of developing sensitization to HLA (cRF > 15%). AMS, EpMS, and EMS were independently associated with the development of HLA?DR and HLA?DQ DSA, but only EMS correlated with the risk of HLA?A and ?B DSA development. Differences in donor?recipient HLA amino?acid sequence and physicochemical properties enable better assessment of the risk of HLA?specific sensitization than conventional HLA matching. Twit Text FOAVip Alloantibody Responses After Renal Transplant Failure Can Be Better Predicted by Donor Recipient HLA Amino Acid Sequence and Physicochemical Disparities Than Conventional HLA Matching ????Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=26755448 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26755448 #FOAvip English Wikipedia <ref>{{Cite pmid|26755448}}</ref> Alloantibody Responses After Renal Transplant Failure Can Be Better Predicted by Donor?Recipient HLA Amino Acid Sequence and Physicochemical Disparities Than Conventional HLA Matching #MMPMID26755448 Kosmoliaptsis V; Mallon DH; Chen Y; Bolton EM; Bradley JA; Taylor CJ Am J Transplant 2016[Jul]; 16 (7): 2139-47 PMID26755448show ga We have assessed whether HLA immunogenicity as defined by differences in donor?recipient HLA amino?acid sequence (amino?acid mismatch score, AMS; and eplet mismatch score, EpMS) and physicochemical properties (electrostatic mismatch score, EMS) enables prediction of allosensitization to HLA, and also prediction of the risk of an individual donor?recipient HLA mismatch to induce donor?specific antibody (DSA). HLA antibody screening was undertaken using single?antigen beads in 131 kidney transplant recipients returning to the transplant waiting list following first graft failure. The effect of AMS, EpMS, and EMS on the development of allosensitization (calculated reaction frequency [cRF]) and DSA was determined. Multivariate analyses, adjusting for time on the waiting list, maintenance on immunosuppression after transplant failure, and graft nephrectomy, showed that AMS (odds ratio [OR]: 1.44 per 10 units, 95% CI: 1.02?2.10, p = 0.04) and EMS (OR: 1.27 per 10 units, 95% CI: 1.02?1.62, p = 0.04) were independently associated with the risk of developing sensitization to HLA (cRF > 15%). AMS, EpMS, and EMS were independently associated with the development of HLA?DR and HLA?DQ DSA, but only EMS correlated with the risk of HLA?A and ?B DSA development. Differences in donor?recipient HLA amino?acid sequence and physicochemical properties enable better assessment of the risk of HLA?specific sensitization than conventional HLA matching. äAlloantibody Responses After Renal Transplant Failure Can Be Better Pr(epmc).pdf DeepDyve Pubget Overpricing