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10.1083/jcb.201607005 http://scihub22266oqcxt.onion/10.1083/jcb.201607005 C5021098!5021098!27621362     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Biol 2016 ; 214 (6): 653-64 Nephropedia Template TP {{tp|p=27621362|t=2016. The lysosome as a command-and-control center for cellular metabolism |pdf=|usr=}}{{27621362}} gab.com Text The lysosome as a command-and-control center for cellular metabolism JO: J Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=27621362 #FOAvip Lysosomes are membrane-bound organelles found in every eukaryotic cell. They are widely known as terminal catabolic stations that rid cells of waste products and scavenge metabolic building blocks that sustain essential biosynthetic reactions during starvation. In recent years, this classical view has been dramatically expanded by the discovery of new roles of the lysosome in nutrient sensing, transcriptional regulation, and metabolic homeostasis. These discoveries have elevated the lysosome to a decision-making center involved in the control of cellular growth and survival. Here we review these recently discovered properties of the lysosome, with a focus on how lysosomal signaling pathways respond to external and internal cues and how they ultimately enable metabolic homeostasis and cellular adaptation. Twit Text FOAVip The lysosome as a command-and-control center for cellular metabolism ????J Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=27621362 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27621362 #FOAvip English Wikipedia <ref>{{Cite pmid|27621362}}</ref> The lysosome as a command-and-control center for cellular metabolism #MMPMID27621362 Lim CY; Zoncu R J Cell Biol 2016[Sep]; 214 (6): 653-64 PMID27621362show ga Lysosomes are membrane-bound organelles found in every eukaryotic cell. They are widely known as terminal catabolic stations that rid cells of waste products and scavenge metabolic building blocks that sustain essential biosynthetic reactions during starvation. In recent years, this classical view has been dramatically expanded by the discovery of new roles of the lysosome in nutrient sensing, transcriptional regulation, and metabolic homeostasis. These discoveries have elevated the lysosome to a decision-making center involved in the control of cellular growth and survival. Here we review these recently discovered properties of the lysosome, with a focus on how lysosomal signaling pathways respond to external and internal cues and how they ultimately enable metabolic homeostasis and cellular adaptation. äThe lysosome as a command-and-control center for cellular metabolism (epmc).pdf DeepDyve Pubget Overpricing