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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Pediatr+Genet
2013 ; 2
(1
): 21-4
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Newborn measles antibody profile in a teaching hospital: Can sex of babies
determine measles IgG acquisition from their respective mothers?
#MMPMID27625835
Ahmadu BU
; Yakubu M
; Abdullahi IB
; Pwavimbo AJ
; Mahmud TA
; Clapton DH
J Pediatr Genet
2013[Mar]; 2
(1
): 21-4
PMID27625835
show ga
Known sex specific differences in fetal, neonatal morbidity and mortality have
been documented. Sex differences also exist in birth-weight centile with males
being larger than females at birth. However, these sex differences are not fully
explored when studying passive measles immunity acquired by babies from their
mothers. Moreover, the mechanisms that confer these sex differences are to a
large extent unknown. Therefore, this study assessed sex of babies as a
determinant of measles immunoglobulin G acquisition from their respective
mothers. One hundred and seventy four newborn babies were enrolled in this study.
Enzyme linked immunosorbent assay was used to measure maternal measles antibodies
(MMA) from sera collected from these babies at birth. Gestational age of the
newborn babies was determined using the Nagele rule, ultrasound scan reports and
the Dubowitz criteria. Sex and mean MMA of these babies was compared using the
Student's t test. Significant comparison existed between mean MMA and sex of post
term babies (P = 0.000), such that post term males had higher levels of MMA than
females. However, overall sex and mean MMA comparison of these babies was not
significant (P = 0.977). There were more MMA in male post term babies relative to
their female peers; however, overall sex comparison of MMA was not significant.
Therefore, there is the need for further study.
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