Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27660422
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27660422
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Patient+Prefer+Adherence
2016 ; 10
(ä): 1727-37
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Self-administered C1 esterase inhibitor concentrates for the management of
hereditary angioedema: usability and patient acceptance
#MMPMID27660422
Li HH
Patient Prefer Adherence
2016[]; 10
(ä): 1727-37
PMID27660422
show ga
Hereditary angioedema (HAE) is a rare genetic disease characterized by episodic
subcutaneous or submucosal swelling. The primary cause for the most common form
of HAE is a deficiency in functional C1 esterase inhibitor (C1-INH). The swelling
caused by HAE can be painful, disfiguring, and life-threatening. It reduces daily
function and compromises the quality of life of affected individuals and their
caregivers. Among different treatment strategies, replacement with C1-INH
concentrates is employed for on-demand treatment of acute attacks and long-term
prophylaxis. Three human plasma-derived C1-INH preparations are approved for HAE
treatment in the US, the European Union, or both regions: Cinryze(®),
Berinert(®), and Cetor(®); however, only Cinryze is approved for long-term
prophylaxis. Postmarketing studies have shown that home therapy
(self-administered or administered by a caregiver) is a convenient and safe
option preferred by many HAE patients. In this review, we summarize the role of
self-administered plasma-derived C1-INH concentrate therapy with Cinryze at home
in the prophylaxis of HAE.