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10.1128/JB.00017-16 http://scihub22266oqcxt.onion/10.1128/JB.00017-16 C5019066!5019066!27068589     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Bacteriol 2016 ; 198 (19): 2572-8 Nephropedia Template TP {{tp|p=27068589|t=2016. Antibiofilm Peptides: Potential as Broad-Spectrum Agents |pdf=|usr=}}{{27068589}} gab.com Text Antibiofilm Peptides: Potential as Broad-Spectrum Agents JO: J Bacteriol http://www.kidney.de/pget.php?&tw=1&pmid=27068589 #FOAvip The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic resistance and relatively few novel compounds or strategies under development or entering the clinic. Bacteria frequently grow on surfaces as biofilm communities encased in a polymeric matrix. The biofilm mode of growth is associated with 65 to 80% of all clinical infections. It causes broad adaptive changes; biofilm bacteria are especially (10- to 1,000-fold) resistant to conventional antibiotics and to date no antimicrobials have been developed specifically to treat biofilms. Small synthetic peptides with broad-spectrum antibiofilm activity represent a novel approach to treat biofilm-related infections. Recent developments have provided evidence that these peptides can inhibit even developed biofilms, kill multiple bacterial species in biofilms (including the ESKAPE [Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species] pathogens), show strong synergy with several antibiotics, and act by targeting a universal stress response in bacteria. Thus, these peptides represent a promising alternative treatment to conventional antibiotics and work effectively in animal models of biofilm-associated infections. Twit Text FOAVip Antibiofilm Peptides: Potential as Broad-Spectrum Agents ????J Bacteriol http://www.kidney.de/pget.php?&tw=1&pmid=27068589 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27068589 #FOAvip English Wikipedia <ref>{{Cite pmid|27068589}}</ref> Antibiofilm Peptides: Potential as Broad-Spectrum Agents #MMPMID27068589 Pletzer D; Hancock REW J Bacteriol 2016[Oct]; 198 (19): 2572-8 PMID27068589show ga The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic resistance and relatively few novel compounds or strategies under development or entering the clinic. Bacteria frequently grow on surfaces as biofilm communities encased in a polymeric matrix. The biofilm mode of growth is associated with 65 to 80% of all clinical infections. It causes broad adaptive changes; biofilm bacteria are especially (10- to 1,000-fold) resistant to conventional antibiotics and to date no antimicrobials have been developed specifically to treat biofilms. Small synthetic peptides with broad-spectrum antibiofilm activity represent a novel approach to treat biofilm-related infections. Recent developments have provided evidence that these peptides can inhibit even developed biofilms, kill multiple bacterial species in biofilms (including the ESKAPE [Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species] pathogens), show strong synergy with several antibiotics, and act by targeting a universal stress response in bacteria. Thus, these peptides represent a promising alternative treatment to conventional antibiotics and work effectively in animal models of biofilm-associated infections. äAntibiofilm Peptides: Potential as Broad-Spectrum Agents (epmc).pdf DeepDyve Pubget Overpricing