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10.1038/srep33226 http://scihub22266oqcxt.onion/10.1038/srep33226 C5018967!5018967 !27615411     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27615411 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2016 ; 6 (ä): 33226 Nephropedia Template TP {{tp|p=27615411 |t=2016. Pirfenidone in patients with rapidly progressive interstitial lung disease associated with clinically amyopathic dermatomyositis |pdf=|usr=}}{{27615411 }} gab.com Text Pirfenidone in patients with rapidly progressive interstitial lung disease associated with clinically amyopathic dermatomyositis JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27615411 #FOAvip To evaluate the efficacy of pirfenidone in patients with rapidly progressive interstitial lung disease (RPILD) related to clinically amyopathic dermatomyositis (CADM), we conducted an open-label, prospective study with matched retrospective controls. Thirty patients diagnosed with CADM-RPILD with a disease duration <6?months at Renji Hospital South Campus from June 2014 to November 2015 were prospectively enrolled and treated with pirfenidone at a target dose of 1800?mg/d in addition to conventional treatment, such as a glucocorticoid and/or other immunosuppressants. Matched patients without pirfenidone treatment (n?=?27) were retrospectively selected as controls between October 2012 and September 2015. We found that the pirfenidone add-on group displayed a trend of lower mortality compared with the control group (36.7% vs 51.9%, p?=?0.2226). Furthermore, the subgroup analysis indicated that the pirfenidone add-on had no impact on the survival of acute ILD patients (disease duration <3?months) (50% vs 50%, p?=?0.3862); while for subacute ILD patients (disease duration 3-6?months), the pirfenidone add-on (n?=?10) had a significantly higher survival rate compared with the control subgroup (n?=?9) (90% vs 44.4%, p?=?0.0450). Our data indicated that the pirfenidone add-on may improve the prognosis of patients with subacute ILD related to CADM. Twit Text FOAVip Pirfenidone in patients with rapidly progressive interstitial lung disease associated with clinically amyopathic dermatomyositis ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27615411 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27615411 #FOAvip English Wikipedia <ref>{{Cite pmid|27615411 }}</ref> Pirfenidone in patients with rapidly progressive interstitial lung disease associated with clinically amyopathic dermatomyositis #MMPMID27615411 Li T ; Guo L ; Chen Z ; Gu L ; Sun F ; Tan X ; Chen S ; Wang X ; Ye S Sci Rep 2016[Sep]; 6 (ä): 33226 PMID27615411 show ga To evaluate the efficacy of pirfenidone in patients with rapidly progressive interstitial lung disease (RPILD) related to clinically amyopathic dermatomyositis (CADM), we conducted an open-label, prospective study with matched retrospective controls. Thirty patients diagnosed with CADM-RPILD with a disease duration <6?months at Renji Hospital South Campus from June 2014 to November 2015 were prospectively enrolled and treated with pirfenidone at a target dose of 1800?mg/d in addition to conventional treatment, such as a glucocorticoid and/or other immunosuppressants. Matched patients without pirfenidone treatment (n?=?27) were retrospectively selected as controls between October 2012 and September 2015. We found that the pirfenidone add-on group displayed a trend of lower mortality compared with the control group (36.7% vs 51.9%, p?=?0.2226). Furthermore, the subgroup analysis indicated that the pirfenidone add-on had no impact on the survival of acute ILD patients (disease duration <3?months) (50% vs 50%, p?=?0.3862); while for subacute ILD patients (disease duration 3-6?months), the pirfenidone add-on (n?=?10) had a significantly higher survival rate compared with the control subgroup (n?=?9) (90% vs 44.4%, p?=?0.0450). Our data indicated that the pirfenidone add-on may improve the prognosis of patients with subacute ILD related to CADM. |Adult [MESH] |Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use [MESH] |Dermatomyositis/complications/*drug therapy/mortality [MESH] |Disease Progression [MESH] |Female [MESH] |Humans [MESH] |Kaplan-Meier Estimate [MESH] |Lung Diseases, Interstitial/*drug therapy/etiology/mortality/pathology [MESH] |Male [MESH] |Middle Aged [MESH] |Prospective Studies [MESH] |Pyridones/*therapeutic use [MESH] |Retrospective Studies [MESH]Pirfenidone in patients with rapidly progressive interstitial lung dis(epmc).pdf DeepDyve Pubget Overpricing