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10.1073/pnas.1601895113 http://scihub22266oqcxt.onion/10.1073/pnas.1601895113 C5018795!5018795!27528682     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (36): 10085-90 Nephropedia Template TP {{tp|p=27528682|t=2016. Cell autonomous regulation of herpes and influenza virus infection by the circadian clock |pdf=|usr=}}{{27528682}} gab.com Text Cell autonomous regulation of herpes and influenza virus infection by the circadian clock JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27528682 #FOAvip The circadian clock coordinates our physiology. Circadian disruption, as occurs during shift work, increases the risk of chronic diseases. For infectious diseases, circadian regulation of systemic immunity seems to underpin ?time-of-day? differences in responses to extracellular pathogens. However, circadian rhythms are cell autonomous, and their interaction with intracellular pathogens, such as viruses, is poorly understood. We demonstrate that time of day of virus infection has a major impact on disease progression, in cellular models as well as in animals, highlighting the key role that cellular clocks play in this phenomenon. Clock disruption leads to increased virus replication and dissemination, indicating that severity of acute infections is influenced by circadian timekeeping. Twit Text FOAVip Cell autonomous regulation of herpes and influenza virus infection by the circadian clock ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27528682 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27528682 #FOAvip English Wikipedia <ref>{{Cite pmid|27528682}}</ref> Cell autonomous regulation of herpes and influenza virus infection by the circadian clock #MMPMID27528682 Edgar RS; Stangherlin A; Nagy AD; Nicoll MP; Efstathiou S; O?Neill JS; Reddy AB Proc Natl Acad Sci U S A 2016[Sep]; 113 (36): 10085-90 PMID27528682show ga The circadian clock coordinates our physiology. Circadian disruption, as occurs during shift work, increases the risk of chronic diseases. For infectious diseases, circadian regulation of systemic immunity seems to underpin ?time-of-day? differences in responses to extracellular pathogens. However, circadian rhythms are cell autonomous, and their interaction with intracellular pathogens, such as viruses, is poorly understood. We demonstrate that time of day of virus infection has a major impact on disease progression, in cellular models as well as in animals, highlighting the key role that cellular clocks play in this phenomenon. Clock disruption leads to increased virus replication and dissemination, indicating that severity of acute infections is influenced by circadian timekeeping. äCell autonomous regulation of herpes and influenza virus infection by (epmc).pdf DeepDyve Pubget Overpricing