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10.1371/journal.pone.0162412 http://scihub22266oqcxt.onion/10.1371/journal.pone.0162412 C5017725!5017725!27612193     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2016 ; 11 (9): ä Nephropedia Template TP {{tp|p=27612193|t=2016. Prodigiosin - A Multifaceted Escherichia coli Antimicrobial Agent |pdf=|usr=}}{{27612193}} gab.com Text Prodigiosin - A Multifaceted Escherichia coli Antimicrobial Agent JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=27612193 #FOAvip Despite a considerable interest in prodigiosin, the mechanism of its antibacterial activity is still poorly understood. In this work, Escherichia coli cells were treated with prodigiosin to determine its antimicrobial effect on bacterial physiology. The effect of prodigiosin was concentration dependent. In prodigiosin treated cells above MIC value no significant DNA damage or cytoplasmic membrane disintegration was observed. The outer membrane, however, becomes leaky. Cells had severely decreased respiration activity. In prodigiosin treated cells protein and RNA synthesis were inhibited, cells were elongated but could not divide. Pre-treatment with prodigiosin improved E. coli survival rate in media containing ampicillin, kanamycin and erythromycin but not phleomycin. The results suggest that prodigiosin acts as a bacteriostatic agent in E. coli cells. If prodigiosin was diluted, cells resumed growth. The results indicate that prodigiosin has distinct mode of antibacterial action in different bacteria. Twit Text FOAVip Prodigiosin - A Multifaceted Escherichia coli Antimicrobial Agent ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=27612193 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27612193 #FOAvip English Wikipedia <ref>{{Cite pmid|27612193}}</ref> Prodigiosin - A Multifaceted Escherichia coli Antimicrobial Agent #MMPMID27612193 Danev?i? T; Bori? Vezjak M; Zorec M; Stopar D PLoS One 2016[]; 11 (9): ä PMID27612193show ga Despite a considerable interest in prodigiosin, the mechanism of its antibacterial activity is still poorly understood. In this work, Escherichia coli cells were treated with prodigiosin to determine its antimicrobial effect on bacterial physiology. The effect of prodigiosin was concentration dependent. In prodigiosin treated cells above MIC value no significant DNA damage or cytoplasmic membrane disintegration was observed. The outer membrane, however, becomes leaky. Cells had severely decreased respiration activity. In prodigiosin treated cells protein and RNA synthesis were inhibited, cells were elongated but could not divide. Pre-treatment with prodigiosin improved E. coli survival rate in media containing ampicillin, kanamycin and erythromycin but not phleomycin. The results suggest that prodigiosin acts as a bacteriostatic agent in E. coli cells. If prodigiosin was diluted, cells resumed growth. The results indicate that prodigiosin has distinct mode of antibacterial action in different bacteria. äProdigiosin - A Multifaceted Escherichia coli Antimicrobial Agent (epmc).pdf DeepDyve Pubget Overpricing