Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s40246-016-0085-z http://scihub22266oqcxt.onion/10.1186/s40246-016-0085-z C5016954!5016954!27608623     free     free     free       Hum+Genomics 2016 ; 10 (1): ä Nephropedia Template TP {{tp|p=27608623|t=2016. MicroRNAs in acute kidney injury |pdf=|usr=}}{{27608623}} gab.com Text MicroRNAs in acute kidney injury JO: Hum Genomics http://www.kidney.de/pget.php?&tw=1&pmid=27608623 #FOAvip Acute kidney injury (AKI) is an important clinical issue that is associated with significant morbidity and mortality. Despite research advances over the past decades, the complex pathophysiology of AKI is not fully understood. The regulatory mechanisms underlying post-AKI repair and fibrosis have not been clarified either. Furthermore, there is no definitively effective treatment for AKI. MicroRNAs (miRNAs) are endogenous single-stranded noncoding RNAs of 19~23 nucleotides that have been shown to be crucial to the post-transcriptional regulation of various cellular biological functions, including proliferation, differentiation, metabolism, and apoptosis. In addition to being fundamental to normal development and physiology, miRNAs also play important roles in various human diseases. In AKI, some miRNAs appear to act pathogenically by promoting inflammation, apoptosis, and fibrosis, while others may act protectively by exerting anti-inflammatory, anti-apoptotic, anti-fibrotic, and pro-angiogenic effects. Thus, miRNAs have not only emerged as novel biomarkers for AKI; they also hold promise to be potential therapeutic targets. Twit Text FOAVip MicroRNAs in acute kidney injury ????Hum Genomics http://www.kidney.de/pget.php?&tw=1&pmid=27608623 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27608623 #FOAvip English Wikipedia <ref>{{Cite pmid|27608623}}</ref> MicroRNAs in acute kidney injury #MMPMID27608623 Fan PC; Chen CC; Chen YC; Chang YS; Chu PH Hum Genomics 2016[]; 10 (1): ä PMID27608623show ga Acute kidney injury (AKI) is an important clinical issue that is associated with significant morbidity and mortality. Despite research advances over the past decades, the complex pathophysiology of AKI is not fully understood. The regulatory mechanisms underlying post-AKI repair and fibrosis have not been clarified either. Furthermore, there is no definitively effective treatment for AKI. MicroRNAs (miRNAs) are endogenous single-stranded noncoding RNAs of 19~23 nucleotides that have been shown to be crucial to the post-transcriptional regulation of various cellular biological functions, including proliferation, differentiation, metabolism, and apoptosis. In addition to being fundamental to normal development and physiology, miRNAs also play important roles in various human diseases. In AKI, some miRNAs appear to act pathogenically by promoting inflammation, apoptosis, and fibrosis, while others may act protectively by exerting anti-inflammatory, anti-apoptotic, anti-fibrotic, and pro-angiogenic effects. Thus, miRNAs have not only emerged as novel biomarkers for AKI; they also hold promise to be potential therapeutic targets. äMicroRNAs in acute kidney injury (epmc).pdf DeepDyve Pubget Overpricing