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10.1182/blood-2016-05-714535

http://scihub22266oqcxt.onion/10.1182/blood-2016-05-714535
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C5016708!5016708!27485827
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suck abstract from ncbi


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pmid27485827      Blood 2016 ; 128 (10): 1424-35
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  • miR-146b antagomir?treated human Tregs acquire increased GVHD inhibitory potency #MMPMID27485827
  • Lu Y; Hippen KL; Lemire AL; Gu J; Wang W; Ni X; Ranganathan P; Levine BL; Riley JL; June CH; Turka LA; Munn DH; Garzon R; Lu L; Blazar BR
  • Blood 2016[Sep]; 128 (10): 1424-35 PMID27485827show ga
  • tTregs express high miR-146b levels and downregulate TRAF6 mRNA and NF-?B activation, which is essential for tTreg function.miR-146b antagomir enhances in vitro and in vivo tTreg suppression and persistence as well as xenogenic GVHD lethality.
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