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10.1007/s11888-016-0335-4 http://scihub22266oqcxt.onion/10.1007/s11888-016-0335-4 C5016547!5016547!27656116     free     free     free       Curr+Colorectal+Cancer+Rep 2016 ; 12 (5): 281-7 Nephropedia Template TP {{tp|p=27656116|t=2016. Organoids as a Model for Colorectal Cancer |pdf=|usr=}}{{27656116}} gab.com Text Organoids as a Model for Colorectal Cancer JO: Curr Colorectal Cancer Rep http://www.kidney.de/pget.php?&tw=1&pmid=27656116 #FOAvip Modelling human diseases in in vitro systems is undisputedly an invaluable research tool, yet there are many limitations. Some of those limitations have been overcome through the introduction of organoid culture systems, which have revolutionised colorectal cancer research and enabled an array of new experimental techniques. This 3D system models the physiology, shape, dynamics and cell make-up of the intestinal epithelium producing a relevant and highly adaptable model system. The increased functional relevance of this model compared to the use of 2D cancer cell lines makes it an invaluable tool for both basic and translational research. As the limitations of this system are being overcome to make high-throughput assays possible, it is clear that organoids are becoming a mainstay of colorectal cancer research. This review aims to explore the advantages and limitations of this system and discusses the future directions enabled by this model. Twit Text FOAVip Organoids as a Model for Colorectal Cancer ????Curr Colorectal Cancer Rep http://www.kidney.de/pget.php?&tw=1&pmid=27656116 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27656116 #FOAvip English Wikipedia <ref>{{Cite pmid|27656116}}</ref> Organoids as a Model for Colorectal Cancer #MMPMID27656116 Young M; Reed KR Curr Colorectal Cancer Rep 2016[]; 12 (5): 281-7 PMID27656116show ga Modelling human diseases in in vitro systems is undisputedly an invaluable research tool, yet there are many limitations. Some of those limitations have been overcome through the introduction of organoid culture systems, which have revolutionised colorectal cancer research and enabled an array of new experimental techniques. This 3D system models the physiology, shape, dynamics and cell make-up of the intestinal epithelium producing a relevant and highly adaptable model system. The increased functional relevance of this model compared to the use of 2D cancer cell lines makes it an invaluable tool for both basic and translational research. As the limitations of this system are being overcome to make high-throughput assays possible, it is clear that organoids are becoming a mainstay of colorectal cancer research. This review aims to explore the advantages and limitations of this system and discusses the future directions enabled by this model. äOrganoids as a Model for Colorectal Cancer (epmc).pdf DeepDyve Pubget Overpricing