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10.3851/IMP3040

http://scihub22266oqcxt.onion/10.3851/IMP3040
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C5016206!5016206!26954372
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suck abstract from ncbi


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pmid26954372      Antivir+Ther 2016 ; 21 (6): 553-8
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  • Tenofovir Alafenamide as Part of a Salvage Regimen in A Patient with Multi-Drug Resistant HIV and Tenofovir DF-Associated Renal Tubulopathy #MMPMID26954372
  • Mikula JM; Manion MM; Maldarelli F; Suarez LM; Norman-Wheeler JF; Ober AG; Dewar RL; Kopp JB; Lane HC; Pau AK
  • Antivir Ther 2016[]; 21 (6): 553-8 PMID26954372show ga
  • We describe a patient with two recent episodes of tenofovir disoproxil fumarate (TDF)-associated acute kidney injury and six-class drug-resistant HIV infection who achieved and maintained viral suppression without worsening kidney function on a regimen including tenofovir alafenamide (TAF) through 48 weeks of therapy. The safety and efficacy of TAF in patients with TDF-associated renal tubulopathy and multiple drug resistance HIV has not yet been described. TAF may represent a useful option to maximally suppress HIV in patients with these complications.
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