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10.1080/15476286.2016.1201628

http://scihub22266oqcxt.onion/10.1080/15476286.2016.1201628
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C5013988!5013988!27351695
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suck abstract from ncbi

pmid27351695      RNA+Biol 2016 ; 13 (9): 756-9
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  • m6A: Signaling for mRNA splicing #MMPMID27351695
  • Adhikari S; Xiao W; Zhao YL; Yang YG
  • RNA Biol 2016[Sep]; 13 (9): 756-9 PMID27351695show ga
  • Among myriads of distinct chemical modifications in RNAs, dynamic N6-methyladenosine (m6A) is one of the most prevalent modifications in eukaryotic mRNAs and non-coding RNAs. Similar to the critical role of chemical modifications in regulation of DNA and protein activities, RNA m6A modification is also observed to be involved in the regulation of diverse functions of RNAs including meiosis, fertility, development, cell reprogramming and circadian period. The RNA m6A modification is recognized by YTH domain containing family proteins comprising of YTHDC1-2 and YTHDF1-3. Here we focus on the nuclear m6A reader YTHDC1 and its regulatory role in alternative splicing and other RNA metabolic processes.
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