Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.1107/S2059798316012237

http://scihub22266oqcxt.onion/10.1107/S2059798316012237
suck pdf from google scholar
C5013595!5013595 !27599734
unlimited free pdf from europmc27599734
    free
PDF from PMC    free
html from PMC    free

suck abstract from ncbi


Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27599734 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117
pmid27599734
      Acta+Crystallogr+D+Struct+Biol 2016 ; 72 (Pt 9 ): 1017-25
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • Crystal structure of human interferon-? receptor 2 reveals the structural basis for receptor specificity #MMPMID27599734
  • Mikulecký P ; Zahradník J ; Kolenko P ; ?erný J ; Charnavets T ; Kolá?ová L ; Ne?asová I ; Pham PN ; Schneider B
  • Acta Crystallogr D Struct Biol 2016[Sep]; 72 (Pt 9 ): 1017-25 PMID27599734 show ga
  • Interferon-? receptor 2 is a cell-surface receptor that is required for interferon-? signalling and therefore plays a critical immunoregulatory role in innate and adaptive immunity against viral and also bacterial and protozoal infections. A crystal structure of the extracellular part of human interferon-? receptor 2 (IFN?R2) was solved by molecular replacement at 1.8?Ĺ resolution. Similar to other class 2 receptors, IFN?R2 has two fibronectin type III domains. The characteristic structural features of IFN?R2 are concentrated in its N-terminal domain: an extensive ?-cation motif of stacked residues KWRWRH, a NAG-W-NAG sandwich (where NAG stands for N-acetyl-D-glucosamine) and finally a helix formed by residues 78-85, which is unique among class 2 receptors. Mass spectrometry and mutational analyses showed the importance of N-linked glycosylation to the stability of the protein and confirmed the presence of two disulfide bonds. Structure-based bioinformatic analysis revealed independent evolutionary behaviour of both receptor domains and, together with multiple sequence alignment, identified putative binding sites for interferon-? and receptor 1, the ligands of IFN?R2.
  • |Amino Acid Motifs [MESH]
  • |Crystallography, X-Ray [MESH]
  • |Disulfides/chemistry [MESH]
  • |Glycosylation [MESH]
  • |Humans [MESH]
  • |Models, Molecular [MESH]
  • |Protein Conformation [MESH]
  • |Protein Domains [MESH]
  • |Protein Folding [MESH]
  • |Protein Stability [MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    Linkout box