Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27621660
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27621660
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Cosmet+Investig+Dermatol
2016 ; 9
(ä): 233-9
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Assessment of a new biological complex efficacy on dysseborrhea, inflammation,
and Propionibacterium acnes proliferation
#MMPMID27621660
Trompezinski S
; Weber S
; Cadars B
; Larue F
; Ardiet N
; Chavagnac-Bonneville M
; Sayag M
; Jourdan E
Clin Cosmet Investig Dermatol
2016[]; 9
(ä): 233-9
PMID27621660
show ga
INTRODUCTION: Acne vulgaris is a common chronic inflammatory disease of the
pilosebaceous unit triggered by Propionibacterium acnes. A bakuchiol, Ginkgo
biloba extract, and mannitol (BGM) complex has been developed to provide patients
with acne with a specific dermocosmetic to be used adjunctively with conventional
treatments. OBJECTIVE: The aim of these studies was to assess the antibacterial,
anti-inflammatory, and antioxidative potential of BGM complex and its individual
compounds as well as its impact on sebum composition. METHODS: The antibacterial,
anti-inflammatory, and antioxidative potential of BGM complex and its compounds
was assessed through in vitro, ex vivo, and clinical studies. The clinical
benefit of BGM complex formulated in a cream was assessed in subjects prone to
acne through sebum composition analysis and photometric assessments. RESULTS:
Results from the studies showed that the BGM complex has significant
antibacterial, anti-inflammatory, and antioxidative properties. At similar
concentrations, bakuchiol has up to twice the antioxidative potential than
vitamin E. In subjects, BGM complex regulated the sebum composition in acne
patients by increasing the level of sapienic and linolenic acid and reducing the
level of oleic acid. The reduced number of porphyrins on the skin surface showed
that it is also effective against P. acnes. CONCLUSION: BGM complex provides a
complete adjunctive care in patients with acne by targeting etiopathogenic
factors of acne: dysseborrhea, inflammation, and P. acnes proliferation.