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10.1186/s12916-016-0676-5 http://scihub22266oqcxt.onion/10.1186/s12916-016-0676-5 C5011905!5011905!27600683     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Med 2016 ; 14 (1): ä Nephropedia Template TP {{tp|p=27600683|t=2016. Post-mortem assessment in vascular dementia: advances and aspirations |pdf=|usr=}}{{27600683}} gab.com Text Post-mortem assessment in vascular dementia: advances and aspirations JO: BMC Med http://www.kidney.de/pget.php?&tw=1&pmid=27600683 #FOAvip Background: Cerebrovascular lesions are a frequent finding in the elderly population. However, the impact of these lesions on cognitive performance, the prevalence of vascular dementia, and the pathophysiology behind characteristic in vivo imaging findings are subject to controversy. Moreover, there are no standardised criteria for the neuropathological assessment of cerebrovascular disease or its related lesions in human post-mortem brains, and conventional histological techniques may indeed be insufficient to fully reflect the consequences of cerebrovascular disease. Discussion: Here, we review and discuss both the neuropathological and in vivo imaging characteristics of cerebrovascular disease, prevalence rates of vascular dementia, and clinico-pathological correlations. We also discuss the frequent comorbidity of cerebrovascular pathology and Alzheimer?s disease pathology, as well as the difficult and controversial issue of clinically differentiating between Alzheimer?s disease, vascular dementia and mixed Alzheimer?s disease/vascular dementia. Finally, we consider additional novel approaches to complement and enhance current post-mortem assessment of cerebral human tissue. Conclusion: Elucidation of the pathophysiology of cerebrovascular disease, clarification of characteristic findings of in vivo imaging and knowledge about the impact of combined pathologies are needed to improve the diagnostic accuracy of clinical diagnoses. Twit Text FOAVip Post-mortem assessment in vascular dementia: advances and aspirations ????BMC Med http://www.kidney.de/pget.php?&tw=1&pmid=27600683 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27600683 #FOAvip English Wikipedia <ref>{{Cite pmid|27600683}}</ref> Post-mortem assessment in vascular dementia: advances and aspirations #MMPMID27600683 McAleese KE; Alafuzoff I; Charidimou A; De Reuck J; Grinberg LT; Hainsworth AH; Hortobagyi T; Ince P; Jellinger K; Gao J; Kalaria RN; Kovacs GG; Kövari E; Love S; Popovic M; Skrobot O; Taipa R; Thal DR; Werring D; Wharton SB; Attems J BMC Med 2016[]; 14 (1): ä PMID27600683show ga Background: Cerebrovascular lesions are a frequent finding in the elderly population. However, the impact of these lesions on cognitive performance, the prevalence of vascular dementia, and the pathophysiology behind characteristic in vivo imaging findings are subject to controversy. Moreover, there are no standardised criteria for the neuropathological assessment of cerebrovascular disease or its related lesions in human post-mortem brains, and conventional histological techniques may indeed be insufficient to fully reflect the consequences of cerebrovascular disease. Discussion: Here, we review and discuss both the neuropathological and in vivo imaging characteristics of cerebrovascular disease, prevalence rates of vascular dementia, and clinico-pathological correlations. We also discuss the frequent comorbidity of cerebrovascular pathology and Alzheimer?s disease pathology, as well as the difficult and controversial issue of clinically differentiating between Alzheimer?s disease, vascular dementia and mixed Alzheimer?s disease/vascular dementia. Finally, we consider additional novel approaches to complement and enhance current post-mortem assessment of cerebral human tissue. Conclusion: Elucidation of the pathophysiology of cerebrovascular disease, clarification of characteristic findings of in vivo imaging and knowledge about the impact of combined pathologies are needed to improve the diagnostic accuracy of clinical diagnoses. äPost-mortem assessment in vascular dementia: advances and aspirations (epmc).pdf DeepDyve Pubget Overpricing