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10.1016/j.clim.2016.03.003 http://scihub22266oqcxt.onion/10.1016/j.clim.2016.03.003 C5010797!5010797!26948928     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Immunol 2017 ; 177 (ä): 60-9 Nephropedia Template TP {{tp|p=26948928|t=2017. Transcriptional and post-transcriptional regulation of NK cell development and function |pdf=|usr=}}{{26948928}} gab.com Text Transcriptional and post-transcriptional regulation of NK cell development and function JO: Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26948928 #FOAvip Natural killer (NK) cells are specialized innate lymphoid cells that survey against viral infections and malignancy. Numerous advances have improved our understanding of the molecular mechanisms that control NK cell development and function over the past decade. These include both studies on the regulatory effects of transcription factors and translational repression via microRNAs. In this review, we summarize our current knowledge of DNA-binding transcription factors that regulate gene expression and thereby orchestrate NK cell development and activation, with an emphasis on recent discoveries. Additionally, we highlight our understanding of how RNA-bindings microRNAs fine tune the NK cell molecular program. We also underscore the large number of open questions in field that are now being addressed using new technological approaches and genetically engineered model organisms. Ultimately, a deeper understanding of the basic molecular biology of NK cells will facilitate new strategies to manipulate NK cells for the treatment of human disease. Twit Text FOAVip Transcriptional and post-transcriptional regulation of NK cell development and function ????Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26948928 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26948928 #FOAvip English Wikipedia <ref>{{Cite pmid|26948928}}</ref> Transcriptional and post-transcriptional regulation of NK cell development and function #MMPMID26948928 Leong JW; Wagner JA; Ireland AR; Fehniger TA Clin Immunol 2017[Apr]; 177 (ä): 60-9 PMID26948928show ga Natural killer (NK) cells are specialized innate lymphoid cells that survey against viral infections and malignancy. Numerous advances have improved our understanding of the molecular mechanisms that control NK cell development and function over the past decade. These include both studies on the regulatory effects of transcription factors and translational repression via microRNAs. In this review, we summarize our current knowledge of DNA-binding transcription factors that regulate gene expression and thereby orchestrate NK cell development and activation, with an emphasis on recent discoveries. Additionally, we highlight our understanding of how RNA-bindings microRNAs fine tune the NK cell molecular program. We also underscore the large number of open questions in field that are now being addressed using new technological approaches and genetically engineered model organisms. Ultimately, a deeper understanding of the basic molecular biology of NK cells will facilitate new strategies to manipulate NK cells for the treatment of human disease. äTranscriptional and post-transcriptional regulation of NK cell develop(epmc).pdf DeepDyve Pubget Overpricing