Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26670741
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Physiol
2016 ; 594
(17
): 4805-13
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Factors regulating quiescent stem cells: insights from the intestine and other
self-renewing tissues
#MMPMID26670741
Richmond CA
; Shah MS
; Carlone DL
; Breault DT
J Physiol
2016[Sep]; 594
(17
): 4805-13
PMID26670741
show ga
Long-lived and self-renewing adult stem cells (SCs) are essential for homeostasis
in a wide range of tissues and can include both rapidly cycling and quiescent
(q)SC populations. Rapidly cycling SCs function principally during normal tissue
maintenance and are highly sensitive to stress, whereas qSCs exit from their
quiescent state in response to homeostatic imbalance and regenerative pressure.
The regulatory mechanisms underlying the quiescent state include factors
essential for cell cycle control, stress response and survival pathways,
developmental signalling pathways, and post-transcriptional modulation. Here, we
review these regulatory mechanisms citing observations from the intestine and
other self-renewing tissues.