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2016 ; 2016
(ä): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis
and progression of chronic kidney disease
#MMPMID27589965
Krochmal M
; Fernandes M
; Filip S
; Pontillo C
; Husi H
; Zoidakis J
; Mischak H
; Vlahou A
; Jankowski J
Database (Oxford)
2016[]; 2016
(ä): ä PMID27589965
show ga
The peptiCKDdb is a publicly available database platform dedicated to support
research in the field of chronic kidney disease (CKD) through identification of
novel biomarkers and molecular features of this complex pathology. PeptiCKDdb
collects peptidomics and proteomics datasets manually extracted from published
studies related to CKD. Datasets from peptidomics or proteomics, human
case/control studies on CKD and kidney or urine profiling were included. Data
from 114 publications (studies of body fluids and kidney tissue: 26 peptidomics
and 76 proteomics manuscripts on human CKD, and 12 focusing on healthy proteome
profiling) are currently deposited and the content is quarterly updated.
Extracted datasets include information about the experimental setup, clinical
study design, discovery-validation sample sizes and list of differentially
expressed proteins (P-value?0.05). A dedicated interactive web interface,
equipped with multiparametric search engine, data export and visualization tools,
enables easy browsing of the data and comprehensive analysis. In conclusion, this
repository might serve as a source of data for integrative analysis or a
knowledgebase for scientists seeking confirmation of their findings and as such,
is expected to facilitate the modeling of molecular mechanisms underlying CKD and
identification of biologically relevant biomarkers.Database URL:
www.peptickddb.com.