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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2016 ; 95
(35
): e4658
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English Wikipedia
Hypereosinophilic syndrome presenting with multiple organ infiltration and deep
venous thrombosis: A case report and literature review
#MMPMID27583887
Gao SJ
; Wei W
; Chen JT
; Tan YH
; Yu CB
; Litzow MR
; Liu QJ
Medicine (Baltimore)
2016[Aug]; 95
(35
): e4658
PMID27583887
show ga
BACKGROUND: Hypereosinophilic syndrome (HES) can be fatal, particularly when
eosinophils infiltrate vital organs and/or if extensive thrombosis develops.
However there are no standard recommendations for the use of anticoagulant
therapy of HES in the setting of thrombosis. METHODS: We herein present a case of
a 46-year-old female who presented with marked peripheral eosinophilia with
symptoms of multi-organ infiltration and extensive deep venous thrombosis (DVT).
In this case, evaluation was carried out before the diagnosis was established,
and timely standard-dose corticosteroids combined with a new oral anticoagulant
(NOAC) therapy were carried out. RESULTS: These measures resulted in a rapid
response and long-term disease control. CONCLUSION: Although there are no data to
support which anticoagulant is preferred in this setting, this case indicates
that the new oral anticoagulants may play an important role in the treatment of
thrombosis in HES.