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2016 ; 95
(35
): e4234
Nephropedia Template TP
gab.com Text
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Using optical coherence tomography to assess the role of age and region in
corneal epithelium and palisades of vogt
#MMPMID27583846
Lin HC
; Tew TB
; Hsieh YT
; Lin SY
; Chang HW
; Hu FR
; Chen WL
Medicine (Baltimore)
2016[Aug]; 95
(35
): e4234
PMID27583846
show ga
Using spectral-domain optical coherence tomography (OCT) to observe the
morphology and epithelial thickness (ET) of the palisades of Vogt (POV), and to
evaluate the role of age and region on these structures.One hundred twelve eyes
of 112 healthy subjects were enrolled and divided into 4 groups: A (0-19), B
(20-39), C (40-59), and D (?60 years old). RTvue-100 OCT was applied on the
cornea and the limbus. The morphology of the subepithelial stroma underneath the
epithelium of POV was classified into typical and atypical types. Maximum ET of
POV was measured manually from OCT images.The positive rate of typical POV in
superior, nasal, temporal, and inferior limbus was: Group A: 100%, 69.2%, 65.4%,
100%; Group B: 100%, 73.5%, 61.8%, 94.1%; Group C: 95.8%, 41.7%, 37.5%, 83.3%;
Group D: 67.9%, 0%, 3.6%, 25%, showing a significant decreasing tendency with
age. The maximum ET of POV in superior, nasal, temporal, and inferior limbus was:
Group A: 103.5?±?10.1 um, 89.2?±?9.7 um, 87.9?±?13.6 um, 104.7?±?14.1 um; Group
B: 111.4?±?15.8 um, 85.3?±?9.9 um, 88.2?±?8.6 um, 112.6?±?19.7 um; Group C:
116.4?±?16.4 um, 82.8?±?11.6 um, 87.0?±?11.6 um, 120.0?±?25.6 um; Group D:
96.3?±?17.9 um, 73.8?±?15.9 um, 79.2?±?16.7 um, 87.4?±?18.5 um. Age-dependent
change was observed. In general, the maximum ET of POV in superior/inferior
quadrants was thicker than the other 2 quadrants.Spectral-domain OCT is a useful
tool to observe the limbal microstructure and provide invaluable information.
Aging and anatomic regions had significant effects on the microstructure of these
areas.