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10.1128/mSphere.00199-16 http://scihub22266oqcxt.onion/10.1128/mSphere.00199-16 C5007431!5007431!27602409     free     free     free       mSphere 2016 ; 1 (4): ä Nephropedia Template TP {{tp|p=27602409|t=2016. Extreme Dysbiosis of the Microbiome in Critical Illness |pdf=|usr=}}{{27602409}} gab.com Text Extreme Dysbiosis of the Microbiome in Critical Illness JO: mSphere http://www.kidney.de/pget.php?&tw=1&pmid=27602409 #FOAvip Critical illness may be associated with the loss of normal, ?health promoting? bacteria, allowing overgrowth of disease-promoting pathogenic bacteria (dysbiosis), which, in turn, makes patients susceptible to hospital-acquired infections, sepsis, and organ failure. This has significant world health implications, because sepsis is becoming a leading cause of death worldwide, and hospital-acquired infections contribute to significant illness and increased costs. Thus, a trial that monitors the ICU patient microbiome to confirm and characterize this hypothesis is urgently needed. Our study analyzed the microbiomes of 115 critically ill subjects and demonstrated rapid dysbiosis from unexpected environmental sources after ICU admission. These data may provide the first steps toward defining targeted therapies that correct potentially ?illness-promoting? dysbiosis with probiotics or with targeted, multimicrobe synthetic ?stool pills? that restore a healthy microbiome in the ICU setting to improve patient outcomes. Twit Text FOAVip Extreme Dysbiosis of the Microbiome in Critical Illness ????mSphere http://www.kidney.de/pget.php?&tw=1&pmid=27602409 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27602409 #FOAvip English Wikipedia <ref>{{Cite pmid|27602409}}</ref> Extreme Dysbiosis of the Microbiome in Critical Illness #MMPMID27602409 McDonald D; Ackermann G; Khailova L; Baird C; Heyland D; Kozar R; Lemieux M; Derenski K; King J; Vis-Kampen C; Knight R; Wischmeyer PE mSphere 2016[Jul]; 1 (4): ä PMID27602409show ga Critical illness may be associated with the loss of normal, ?health promoting? bacteria, allowing overgrowth of disease-promoting pathogenic bacteria (dysbiosis), which, in turn, makes patients susceptible to hospital-acquired infections, sepsis, and organ failure. This has significant world health implications, because sepsis is becoming a leading cause of death worldwide, and hospital-acquired infections contribute to significant illness and increased costs. Thus, a trial that monitors the ICU patient microbiome to confirm and characterize this hypothesis is urgently needed. Our study analyzed the microbiomes of 115 critically ill subjects and demonstrated rapid dysbiosis from unexpected environmental sources after ICU admission. These data may provide the first steps toward defining targeted therapies that correct potentially ?illness-promoting? dysbiosis with probiotics or with targeted, multimicrobe synthetic ?stool pills? that restore a healthy microbiome in the ICU setting to improve patient outcomes. äExtreme Dysbiosis of the Microbiome in Critical Illness (epmc).pdf DeepDyve Pubget Overpricing