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10.1080/2162402X.2016.1182278

http://scihub22266oqcxt.onion/10.1080/2162402X.2016.1182278
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suck abstract from ncbi


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pmid27622039
      Oncoimmunology 2016 ; 5 (7 ): e1182278
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  • The dual role of tumor lymphatic vessels in dissemination of metastases and immune response development #MMPMID27622039
  • Stachura J ; Wachowska M ; Kilarski WW ; Güç E ; Golab J ; Muchowicz A
  • Oncoimmunology 2016[Jul]; 5 (7 ): e1182278 PMID27622039 show ga
  • Lymphatic vasculature plays a crucial role in the immune response, enabling transport of dendritic cells (DCs) and antigens (Ags) into the lymph nodes. Unfortunately, the lymphatic system has also a negative role in the progression of cancer diseases, by facilitating the metastatic spread of many carcinomas to the draining lymph nodes. The lymphatics can promote antitumor immune response as well as tumor tolerance. Here, we review the role of lymphatic endothelial cells (LECs) in tumor progression and immunity and mechanism of action in the newest anti-lymphatic therapies, including photodynamic therapy (PDT).
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