Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27564295
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27564295
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Int+Braz+J+Urol
2016 ; 42
(4
): 810-6
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
The combination of urinary IL - 6 and renal biometry as useful diagnostic tools
to differentiate acute pyelonephritis from lower urinary tract infection
#MMPMID27564295
Azab S
; Zakaria M
; Raafat M
; Seief H
Int Braz J Urol
2016[Jul]; 42
(4
): 810-6
PMID27564295
show ga
OBJECTIVE: To evaluate the role of renal ultrasound (RUS) and urinary IL-6 in the
differentiation between acute pyelonephritis (APN) and lower urinary tract
infection (LUTI). PATIENTS AND METHODS: This prospective study was carried out at
the Pediatric and urology outpatient and inpatient departments of Cairo
University Children's Hospital as well as October 6 University Hospital and it
included 155 children between one month and fourteen years old with positive
culture UTI. Patients were categorized into APN and LUTI based on their clinical
features and laboratory parameters. Thirty healthy children, age and sex matched
constituted the control group. Children with positive urine cultures were treated
with appropriate antibiotics. Before treatment, urinary IL-6 was measured by
enzyme immunoassay technique (ELISA), and renal ultrasound (RUS) was done. CRP
(C-reactive protein), IL-6 and RUS were repeated on the 14th day of antibiotic
treatment to evaluate the changes in their levels in response to treatment.
RESULTS: UIL-6 levels were more significantly higher in patients with APN than in
patients with LUTI (24.3±19.3pg/mL for APN vs. 7.3±2.7pg/mL in LUTI (95% CI:
2.6-27.4; p< 0.01). Similarly, serum CRP was more significantly higher in
patients with APN than in children with LUTI (19.7±9.1?g/mL vs. 5.5±2.3?g/mL (p<
0.01). IL-6 levels >20pg/mL and serum CRP >20?g/mL were highly reliable markers
of APN. Mean renal volume and mean volume difference between the two kidneys in
the APN group were more than that of the LUTI and control groups (P< 0.001).
Renal volume between 120-130% of normal was the best for differentiating APN from
LUTI. CONCLUSIONS: RUS and urinary IL-6 levels have a highly dependable role in
the differentiation between APN and LUTI especially in places where other
investigations are not available and/ or affordable.