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10.1186/s13059-016-1046-5

http://scihub22266oqcxt.onion/10.1186/s13059-016-1046-5
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C5006378!5006378!27582168
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suck abstract from ncbi

pmid27582168      Genome+Biol 2016 ; 17 (1): ä
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  • The epigenome: the next substrate for engineering #MMPMID27582168
  • Park M; Keung AJ; Khalil AS
  • Genome Biol 2016[]; 17 (1): ä PMID27582168show ga
  • We are entering an era of epigenome engineering. The precision manipulation of chromatin and epigenetic modifications provides new ways to interrogate their influence on genome and cell function and to harness these changes for applications. We review the design and state of epigenome editing tools, highlighting the unique regulatory properties afforded by these systems.
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