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2016 ; 6
(ä): 32359
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Patient characteristics and risk factors of early and late death in incident
peritoneal dialysis patients
#MMPMID27576771
Liu X
; Huang R
; Wu H
; Wu J
; Wang J
; Yu X
; Yang X
Sci Rep
2016[Aug]; 6
(ä): 32359
PMID27576771
show ga
This study was conducted to identify key patient characteristics and risk factors
for peritoneal dialysis (PD) mortality in terms of different time-point of death
occurrence. The incident PD patients from January 1, 2006 to December 31, 2013 in
our PD center were recruited and followed up until December 31, 2015. Patients
who died in the early period (the first 3 months) were older, had higher
neutrophil to lymphocyte ratio (N/L), serum phosphorus, and uric acid level, and
had lower diastolic pressure, hemoglobin, serum albumin, and calcium levels.
After adjustment of gender, age, and PD inception, higher N/L level [hazard ratio
(HR) 1.115, P?=?0.006], higher phosphorus lever (HR 1.391, P?0.001), lower
hemoglobin level (HR 0.596, P?0.001), and lower serum albumin level (HR 0.382,
P?=?0.017) were risk factors for early mortality. While, presence of diabetes (HR
1.627, P?=?0.001), presence of cardiovascular disease (HR 1.847, P?0.001) and
lower serum albumin level (HR 0.720, P?=?0.023) were risk factors for late
mortality (over 24 months). In conclusion, patient characteristics and risk
factors associated with early and late mortality in incident PD patients were
different, which indicated specific management according to patient
characteristics at the initiation of PD should be established to improve PD
patient survival.