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10.1080/15384101.2016.1208872 http://scihub22266oqcxt.onion/10.1080/15384101.2016.1208872 C5004685!5004685 !27419533     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27419533 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27419533 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell+Cycle 2016 ; 15 (17 ): 2256-62 Nephropedia Template TP {{tp|p=27419533 |t=2016. Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors |pdf=|usr=}}{{27419533 }} gab.com Text Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors JO: Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=27419533 #FOAvip EZH2, the main catalytic component of the Polycomb Repressive Complex 2 (PRC2) is apparently upregulated in most solid tumors. Furthermore its expression generally associates with poor prognosis. It was proposed that this correlation reflects a causal event, EZH2 mediating the silencing of key tumor suppressor loci. In contrast, we recently showed that EZH2 is dispensable for solid tumor development and that its elevated expression reflects the abnormally high proliferation rate of cancer cells. Here, we investigate the functional association between EZH2 expression and silencing of key tumor suppressor loci and further illustrate the confounding effect of proliferation on EZH2's association to outcome. Twit Text FOAVip Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors ????Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=27419533 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27419533 #FOAvip English Wikipedia <ref>{{Cite pmid|27419533 }}</ref> Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors #MMPMID27419533 Wassef M ; Michaud A ; Margueron R Cell Cycle 2016[Sep]; 15 (17 ): 2256-62 PMID27419533 show ga EZH2, the main catalytic component of the Polycomb Repressive Complex 2 (PRC2) is apparently upregulated in most solid tumors. Furthermore its expression generally associates with poor prognosis. It was proposed that this correlation reflects a causal event, EZH2 mediating the silencing of key tumor suppressor loci. In contrast, we recently showed that EZH2 is dispensable for solid tumor development and that its elevated expression reflects the abnormally high proliferation rate of cancer cells. Here, we investigate the functional association between EZH2 expression and silencing of key tumor suppressor loci and further illustrate the confounding effect of proliferation on EZH2's association to outcome. |*Gene Silencing [MESH] |*Genes, Tumor Suppressor [MESH] |Animals [MESH] |Biomarkers, Tumor/metabolism [MESH] |Cell Line, Transformed [MESH] |Cell Proliferation [MESH] |Cyclin-Dependent Kinase Inhibitor p16/metabolism [MESH] |Enhancer of Zeste Homolog 2 Protein/genetics/*metabolism [MESH] |Humans [MESH] |Mice [MESH] |Models, Biological [MESH] |Neoplasms/*genetics/pathology [MESH]Association between EZH2 expression, silencing of tumor suppressors an(epmc).pdf DeepDyve Pubget Overpricing