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10.3324/haematol.2015.123562

http://scihub22266oqcxt.onion/10.3324/haematol.2015.123562
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C5004414!5004414!26314082
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suck abstract from ncbi


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pmid26314082      Haematologica 2015 ; 100 (8): 997-1004
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  • Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies #MMPMID26314082
  • Lehmberg K; Nichols KE; Henter JI; Girschikofsky M; Greenwood T; Jordan M; Kumar A; Minkov M; La Rosée P; Weitzman S
  • Haematologica 2015[Aug]; 100 (8): 997-1004 PMID26314082show ga
  • The hyperinflammatory syndrome hemophagocytic lymphohistiocytosis can occur in the context of malignancies. Malignancy-triggered hemophagocytic lymphohistiocytosis should be regarded seperately from hemophagocytic lymphohistiocytosis during chemotherapeutic treatment, which is frequently associated with an infectious trigger. The substantial overlap between the features of hemophagocytic lymphohistiocytosis with features of neoplasms makes its identification difficult when it occurs in malignant conditions. To facilitate recognition and diagnostic workup, and provide guidance regarding the treatment of malignancy-associated hemophagocytic lymphohistiocytosis, consensus recommendations were developed by the Study Group on Hemophagocytic Lymphohistiocytosis Subtypes of the Histiocyte Society, an interdisciplinary group consisting of pediatric and adult hemato-oncologists and immunologists.
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