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2016 ; 6
(ä): 32376
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gab.com Text
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English Wikipedia
The use of Haemostatic Agents does not impact the rate of hemorrhagic
complications in patients undergoing partial nephrectomy for renal masses
#MMPMID27572274
Abu-Ghanem Y
; Dotan Z
; Kaver I
; Zilberman DE
; Ramon J
Sci Rep
2016[Aug]; 6
(ä): 32376
PMID27572274
show ga
Hemostatic agents(HAs) have gained increasing popularity as interventions to
improve perioperative haemostasis and diminish the need for allogeneic red cell
transfusion(PBT) despite a paucity of data supporting the practice. The aim of
the current study is to examine the efficacy of HAs in reducing the rate of
hemorrhagic complications during partial nephrectomy(PN). Data on 657 patients,
who underwent elective PN between 2004-2013, were analyzed. The impact of HAs and
SURGICEL was evaluated by comparing four sequential groups of patients:
Group1?=?Sutures alone, Group2?=?sutures and HA, Group3?=?sutures and SURGICEL,
Group4?=?both HA and SURGICEL. Complications included post-operative urinary
leak(UL), PBT rate, delayed bleeding and post-operative renal failure. Results
showed that the use of HAs did not engender a statistically significant
difference in overall complications rate. Specifically, the addition of HAs did
not reduce the rate of PBT, delayed bleeding or UL. Further analysis revealed
that patients who received SURGICEL had significantly higher PBT rate and higher
prevalence of UL cases. Addition of HAs to SURGICEL had no effect on the rate of
these complications. In the current study, the use of HAs during open and
laparoscopic PN did not reduce the rate of negative outcomes. Adequate suture
renorrhaphy may be sufficient to prevent hemorrhagic complications.