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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Can+J+Gastroenterol+Hepatol
2016 ; 2016
(ä): 4123692
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Eosinophilic Esophagitis in Children and Adolescents with Abdominal Pain:
Comparison with EoE-Dysphagia and Functional Abdominal Pain
#MMPMID27610357
Gunasekaran T
; Prabhakar G
; Schwartz A
; Gorla K
; Gupta S
; Berman J
Can J Gastroenterol Hepatol
2016[]; 2016
(ä): 4123692
PMID27610357
show ga
Aim. Compare EoE-AP with EoE-D for clinical, endoscopy (EGD), histology and
outcomes and also with FAP-N. Method. Symptoms, physical findings, EGD,
histology, symptom scores, and treatments were recorded for the three groups.
Cluster analysis was done. Results. Dysphagia and abdominal pain were different
in numbers but not statistically significant between EoE-AP and EoE-D. EGD,
linear furrows, white exudates were more in the EoE-D and both combined were
significant (p < 0.05). EoE-D, peak and mean eosinophils (p??0.06) and
eosinophilic micro abscesses (p??0.001) were higher. Follow-Up. Based on single
symptom, EoE-AP had 30% (p??0.25) improvement, EoE-D 86% (p < 0.001) and similar
with composite score (p??0.57 and <0.001, resp.). Patients who had follow-up,
EGD: 42.8% with EoE-AP and 77.8% with EoE-D, showed single symptom improvement
and the eosinophil count fell from 38.5/34.6 (peak and mean) to 31.2/30.4
(p??0.70) and from 43.6/40.8 to 25.2/22.8 (p < 0.001), respectively. FAP-N
patients had similar symptom improvement like EoE-D. Cluster Analysis. EoE-AP and
FAP-N were similar in clinical features and response to treatment, but EoE-D was
distinctly different from EoE-AP and FAP-N. Conclusion. Our study demonstrates
that EoE-AP and EoE-D have different histology and outcomes. In addition, EoE-AP
has clinical features similar to the FAP-N group.