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10.3390/ijms17081218 http://scihub22266oqcxt.onion/10.3390/ijms17081218 C5000616!5000616 !27472326     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27472326 &cmd=llinks): Failed to open stream: HTTP request failed! 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The Impact of Nonalcoholic Fatty Liver Disease on Renal Function in Children with Overweight/Obesity |pdf=|usr=}}{{27472326 }} gab.com Text The Impact of Nonalcoholic Fatty Liver Disease on Renal Function in Children with Overweight/Obesity JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=27472326 #FOAvip The association between nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease has attracted interest and attention over recent years. However, no data are available in children. We determined whether children with NAFLD show signs of renal functional alterations, as determined by estimated glomerular filtration rate (eGFR) and urinary albumin excretion. We studied 596 children with overweight/obesity, 268 with NAFLD (hepatic fat fraction ?5% on magnetic resonance imaging) and 328 without NAFLD, and 130 healthy normal-weight controls. Decreased GFR was defined as eGFR < 90 mL/min/1.73 m². Abnormal albuminuria was defined as urinary excretion of ?30 mg/24 h of albumin. A greater prevalence of eGFR < 90 mL/min/1.73 m² was observed in patients with NAFLD compared to those without liver involvement and healthy subjects (17.5% vs. 6.7% vs. 0.77%; p < 0.0001). The proportion of children with abnormal albuminuria was also higher in the NAFLD group compared to those without NAFLD, and controls (9.3% vs. 4.0% vs. 0; p < 0.0001). Multivariate logistic regression analysis revealed that NAFLD was associated with decreased eGFR and/or microalbuminuria (odds ratio, 2.54 (confidence interval, 1.16-5.57); p < 0.05) independently of anthropometric and clinical variables. Children with NAFLD are at risk for early renal dysfunction. Recognition of this abnormality in the young may help to prevent the ongoing development of the disease. Twit Text FOAVip The Impact of Nonalcoholic Fatty Liver Disease on Renal Function in Children with Overweight/Obesity ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=27472326 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27472326 #FOAvip English Wikipedia <ref>{{Cite pmid|27472326 }}</ref> The Impact of Nonalcoholic Fatty Liver Disease on Renal Function in Children with Overweight/Obesity #MMPMID27472326 Pacifico L ; Bonci E ; Andreoli GM ; Di Martino M ; Gallozzi A ; De Luca E ; Chiesa C Int J Mol Sci 2016[Jul]; 17 (8 ): ä PMID27472326 show ga The association between nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease has attracted interest and attention over recent years. However, no data are available in children. We determined whether children with NAFLD show signs of renal functional alterations, as determined by estimated glomerular filtration rate (eGFR) and urinary albumin excretion. We studied 596 children with overweight/obesity, 268 with NAFLD (hepatic fat fraction ?5% on magnetic resonance imaging) and 328 without NAFLD, and 130 healthy normal-weight controls. Decreased GFR was defined as eGFR < 90 mL/min/1.73 m². Abnormal albuminuria was defined as urinary excretion of ?30 mg/24 h of albumin. A greater prevalence of eGFR < 90 mL/min/1.73 m² was observed in patients with NAFLD compared to those without liver involvement and healthy subjects (17.5% vs. 6.7% vs. 0.77%; p < 0.0001). The proportion of children with abnormal albuminuria was also higher in the NAFLD group compared to those without NAFLD, and controls (9.3% vs. 4.0% vs. 0; p < 0.0001). Multivariate logistic regression analysis revealed that NAFLD was associated with decreased eGFR and/or microalbuminuria (odds ratio, 2.54 (confidence interval, 1.16-5.57); p < 0.05) independently of anthropometric and clinical variables. Children with NAFLD are at risk for early renal dysfunction. Recognition of this abnormality in the young may help to prevent the ongoing development of the disease. |Case-Control Studies [MESH] |Child [MESH] |Cross-Sectional Studies [MESH] |Female [MESH] |Glomerular Filtration Rate [MESH] |Humans [MESH] |Male [MESH] |Non-alcoholic Fatty Liver Disease/*physiopathology [MESH] |Obesity/*complications [MESH] |Overweight/*complications [MESH] |Prevalence [MESH] |Renal Insufficiency, Chronic/*epidemiology [MESH] |Risk Factors [MESH]The Impact of Nonalcoholic Fatty Liver Disease on Renal Function in Ch(epmc).pdf DeepDyve Pubget Overpricing