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10.3390/cancers8080074 http://scihub22266oqcxt.onion/10.3390/cancers8080074 C4999783!4999783!27527215     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancers+(Basel) 2016 ; 8 (8): ä Nephropedia Template TP {{tp|p=27527215|t=2016. The Role of the C-Clamp in Wnt-Related Colorectal Cancers |pdf=|usr=}}{{27527215}} gab.com Text The Role of the C-Clamp in Wnt-Related Colorectal Cancers JO: Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=27527215 #FOAvip T-cell Factor/Lymphoid Enhancer Factor (TCF/LEF) transcription factors are major regulators of Wnt targets, and the products of the TCF7 and TCF7L2 genes have both been implicated in the progression of colorectal cancer in animal models and humans. TCFs recognize specific DNA sequences through their high mobility group (HMG) domains, but invertebrate TCFs and some isoforms of vertebrate TCF7 and TCF7L2 contain a second DNA binding domain known as the C-clamp. This review will cover the basic properties of C-clamps and their importance in Wnt signaling, using data from Drosophila, C. elegans, and mammalian cell culture. The connection between C-clamp containing TCFs and colorectal cancer will also be discussed. Twit Text FOAVip The Role of the C-Clamp in Wnt-Related Colorectal Cancers ????Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=27527215 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27527215 #FOAvip English Wikipedia <ref>{{Cite pmid|27527215}}</ref> The Role of the C-Clamp in Wnt-Related Colorectal Cancers #MMPMID27527215 Ravindranath AJ; Cadigan KM Cancers (Basel) 2016[Aug]; 8 (8): ä PMID27527215show ga T-cell Factor/Lymphoid Enhancer Factor (TCF/LEF) transcription factors are major regulators of Wnt targets, and the products of the TCF7 and TCF7L2 genes have both been implicated in the progression of colorectal cancer in animal models and humans. TCFs recognize specific DNA sequences through their high mobility group (HMG) domains, but invertebrate TCFs and some isoforms of vertebrate TCF7 and TCF7L2 contain a second DNA binding domain known as the C-clamp. This review will cover the basic properties of C-clamps and their importance in Wnt signaling, using data from Drosophila, C. elegans, and mammalian cell culture. The connection between C-clamp containing TCFs and colorectal cancer will also be discussed. äThe Role of the C-Clamp in Wnt-Related Colorectal Cancers (epmc).pdf DeepDyve Pubget Overpricing