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10.4252/wjsc.v8.i8.243 http://scihub22266oqcxt.onion/10.4252/wjsc.v8.i8.243 C4999651!4999651!27621758     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Stem+Cells 2016 ; 8 (8): 243-50 Nephropedia Template TP {{tp|p=27621758|t=2016. Targeting stem cells by radiation: From the biological angle to clinical aspects |pdf=|usr=}}{{27621758}} gab.com Text Targeting stem cells by radiation: From the biological angle to clinical aspects JO: World J Stem Cells http://www.kidney.de/pget.php?&tw=1&pmid=27621758 #FOAvip Radiotherapy is a cornerstone of anticancer treatment. However in spite of technical evolutions, important rates of failure and of toxicity are still reported. Although numerous pre-clinical data have been published, we address the subject of radiotherapy-stem cells interaction from the clinical efficacy and toxicity perspective. On one side, cancer stem cells (CSCs) have been recently evidenced in most of solid tumor primary locations and are thought to drive radio-resistance phenomena. It is particularly suggested in glioblastoma, where CSCs were showed to be housed in the subventricular zone (SVZ). In recent retrospective studies, the radiation dose to SVZ was identified as an independent factor significantly influencing overall survival. On the other side, healthy tissue stem cells radio-destruction has been recently suggested to cause two of the most quality of life-impacting side effects of radiotherapy, namely memory disorders after brain radiotherapy, and xerostomia after head and neck radiotherapy. Recent publications studying the impact of a radiation dose decrease on healthy brain and salivary stem cells niches suggested significantly reduced long term toxicities. Stem cells comprehension should be a high priority for radiation oncologists, as this particular cell population seems able to widely modulate the efficacy/toxicity ratio of radiotherapy in real life patients. Twit Text FOAVip Targeting stem cells by radiation: From the biological angle to clinical aspects ????World J Stem Cells http://www.kidney.de/pget.php?&tw=1&pmid=27621758 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27621758 #FOAvip English Wikipedia <ref>{{Cite pmid|27621758}}</ref> Targeting stem cells by radiation: From the biological angle to clinical aspects #MMPMID27621758 Vallard A; Espenel S; Guy JB; Diao P; Xia Y; El Meddeb Hamrouni A; Ben Mrad M; Falk AT; Rodriguez-Lafrasse C; Rancoule C; Magné N World J Stem Cells 2016[Aug]; 8 (8): 243-50 PMID27621758show ga Radiotherapy is a cornerstone of anticancer treatment. However in spite of technical evolutions, important rates of failure and of toxicity are still reported. Although numerous pre-clinical data have been published, we address the subject of radiotherapy-stem cells interaction from the clinical efficacy and toxicity perspective. On one side, cancer stem cells (CSCs) have been recently evidenced in most of solid tumor primary locations and are thought to drive radio-resistance phenomena. It is particularly suggested in glioblastoma, where CSCs were showed to be housed in the subventricular zone (SVZ). In recent retrospective studies, the radiation dose to SVZ was identified as an independent factor significantly influencing overall survival. On the other side, healthy tissue stem cells radio-destruction has been recently suggested to cause two of the most quality of life-impacting side effects of radiotherapy, namely memory disorders after brain radiotherapy, and xerostomia after head and neck radiotherapy. Recent publications studying the impact of a radiation dose decrease on healthy brain and salivary stem cells niches suggested significantly reduced long term toxicities. Stem cells comprehension should be a high priority for radiation oncologists, as this particular cell population seems able to widely modulate the efficacy/toxicity ratio of radiotherapy in real life patients. äTargeting stem cells by radiation: From the biological angle to clinic(epmc).pdf DeepDyve Pubget Overpricing