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10.1371/journal.pone.0161958

http://scihub22266oqcxt.onion/10.1371/journal.pone.0161958
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C4999293!4999293!27560377
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suck abstract from ncbi


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pmid27560377      PLoS+One 2016 ; 11 (8): ä
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  • Association of Sjögrens Syndrome in Patients with Chronic Hepatitis Virus Infection: A Population-Based Analysis #MMPMID27560377
  • Yeh CC; Wang WC; Wu CS; Sung FC; Su CT; Shieh YH; Chang SN; Su FH
  • PLoS One 2016[]; 11 (8): ä PMID27560377show ga
  • Objective: The association between Sjögren?s syndrome (SS) and chronic hepatitis virus infection is inconclusive. Hepatitis B (HBV) and hepatitis C virus (HCV) infections are highly prevalent in Taiwan. We used a population-based case-control study to evaluate the associations between SS and HBV and HCV infections. Materials and Methods: We identified 9,629 SS patients without other concomitant autoimmune diseases and 38,516 sex- and age-matched controls without SS from the Taiwan National Health Insurance claims data between 2000 and 2011. We utilized multivariate logistic regression to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of the associations between SS and HBV and HCV infections. Sex- and age-specific (<55 and ?55 years) risks of SS were evaluated. Results: The risk of SS was higher in patients with HCV than in those without chronic viral hepatitis (OR = 2.49, 95% CI = 2.16?2.86). Conversely, HBV infection was not associated with SS (OR = 1.10, 95% CI = 0.98?1.24). Younger HCV patients were at a higher risk for SS (<55 years: OR = 3.37, 95% CI = 2.62?4.35; ?55 years: OR = 2.20, 95% CI = 1.84?2.62). Men with HCV were at a greater risk for SS (women: OR = 2.26, 95% CI = 1.94?2.63; men: OR = 4.22, 95% CI = 2.90?6.16). Only men with chronic HBV exhibited a higher risk of SS (OR = 1.61, 95% CI = 1.21?2.14). Conclusion: HCV infection was associated with SS; however, HBV only associated with SS in men.
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