Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27602144
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27602144
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Oncol+Lett
2016 ; 12
(3
): 2084-2086
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Possible intrinsic association of anti-neutrophil cytoplasmic antibody-associated
vasculitis coexisting with multiple myeloma
#MMPMID27602144
Liu H
; Xiong J
; Zhang J
; Zhang Y
; Nie L
; Wang Y
; Zhao J
Oncol Lett
2016[Sep]; 12
(3
): 2084-2086
PMID27602144
show ga
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a
life-threatening condition that causes renal failure. Multiple myeloma (MM) is a
malignant proliferation of monoclonal plasma cells in the blood that can also
cause renal failure. The two diseases have high morbidity and mortality rates in
the elderly, with a poor prognosis. A 64-year-old female presented to Xinqiao
Hospital (Chonqing, China) with fatigue and a poor appetite that had been
apparent for 6 weeks. Laboratory tests revealed a serum creatinine level of 10.31
mg/dl, a cytoplasmic ANCA titer of 1:10, a positive result for myeloperoxidase
and a serum globulin level of 3.96 g/dl. A renal biopsy revealed crescent
glomerulonephritis, combined with the rapid progression of renal function. Based
on these observations (ANCA titer, crescent glomerulonephritis and rapid
progression of renal function) a diagnosis of AAV was established. MM was
confirmed by serum immunofixation electrophoresis combined with bone marrow
aspiration. The present study discusses what is, to the best of our knowledge,
the first case of AAV coexisting with MM in order to highlight it as a clinical
concern.