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10.1097/MD.0000000000003925

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C4998490!4998490 !27311004
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suck abstract from ncbi


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pmid27311004
      Medicine+(Baltimore) 2016 ; 95 (24 ): e3925
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  • Effect of preservation of Denonvilliers fascia during laparoscopic resection for mid-low rectal cancer on protection of male urinary and sexual functions #MMPMID27311004
  • Wei HB ; Fang JF ; Zheng ZH ; Wei B ; Huang JL ; Chen TF ; Huang Y ; Lei PR
  • Medicine (Baltimore) 2016[Jun]; 95 (24 ): e3925 PMID27311004 show ga
  • The aim of this study was to investigate the effect of preservation of Denonvilliers' fascia (DF) during laparoscopic resection for mid-low rectal cancer on protection of male urogenital function. Whether preservation of DF during TME is effective for protection of urogenital function is largely elusive.Seventy-four cases of male mid-low rectal cancer were included. Radical laparoscopic proctectomy was performed, containing 38 cases of preservation of DF (P-group) and 36 cases of resection of DF (R-group) intraoperatively. Intraoperative electrical nerve stimulation (INS) on pelvic autonomic nerve was performed and intravesical pressure was measured manometrically. Urinary function was evaluated by residual urine volume (RUV), International Prostatic Symptom Score (IPSS), and quality of life (QoL). Sexual function was evaluated using the International Index of Erectile Function (IIEF) scale and ejaculation function classification.Compared with performing INS on the surfaces of prostate and seminal vesicles in the R-group, INS on DF in the P-group exhibited higher increasing intravesical pressure (7.3?±?1.5 vs 5.9?±?2.4?cmH2O, P = 0.008). In addtion, the P-group exhibited lower RUV (34.3?±?27.2 vs 57.1?±?50.7?mL, P = 0.020), lower IPSS and QoL scores (7 days: 6.1?±?2.4 vs 9.5?±?5.9, P = 0.002 and 2.2?±?1.1 vs 2.9?±?1.1, P = 0.005; 1 month: 5.1?±?2.4 vs 6.6?±?2.2, P = 0.006 and 1.6?±?0.7 vs 2.1?±?0.6, P = 0.003, respectively), higher IIEF score (3 months: 10.7?±?2.1 vs 8.9?±?2.0, P = 0.000; 6 months: 14.8?±?2.2 vs 12.9?±?2.2, P = 0.001) and lower incidence of ejaculation dysfunction (3 months: 28.9% vs 52.8%, P = 0.037; 6 months: 18.4% vs 44.4%, P = 0.016) postoperatively.Preservation of DF during laparoscopic resection for selective male mid-low rectal cancer is effective for protection of urogenital function.
  • |Adolescent [MESH]
  • |Adult [MESH]
  • |Aged [MESH]
  • |Colectomy/*methods [MESH]
  • |Fasciotomy/*methods [MESH]
  • |Follow-Up Studies [MESH]
  • |Humans [MESH]
  • |Intraoperative Period [MESH]
  • |Laparoscopy/*methods [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Postoperative Complications/*prevention & control [MESH]
  • |Quality of Life [MESH]
  • |Rectal Neoplasms/*surgery [MESH]
  • |Retrospective Studies [MESH]
  • |Sexual Dysfunction, Physiological/etiology/physiopathology/*prevention & control [MESH]
  • |Sexuality [MESH]
  • |Urination [MESH]
  • |Urination Disorders/etiology/physiopathology/*prevention & control [MESH]


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