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2016 ; 95
(24
): e3925
Nephropedia Template TP
gab.com Text
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English Wikipedia
Effect of preservation of Denonvilliers fascia during laparoscopic resection for
mid-low rectal cancer on protection of male urinary and sexual functions
#MMPMID27311004
Wei HB
; Fang JF
; Zheng ZH
; Wei B
; Huang JL
; Chen TF
; Huang Y
; Lei PR
Medicine (Baltimore)
2016[Jun]; 95
(24
): e3925
PMID27311004
show ga
The aim of this study was to investigate the effect of preservation of
Denonvilliers' fascia (DF) during laparoscopic resection for mid-low rectal
cancer on protection of male urogenital function. Whether preservation of DF
during TME is effective for protection of urogenital function is largely
elusive.Seventy-four cases of male mid-low rectal cancer were included. Radical
laparoscopic proctectomy was performed, containing 38 cases of preservation of DF
(P-group) and 36 cases of resection of DF (R-group) intraoperatively.
Intraoperative electrical nerve stimulation (INS) on pelvic autonomic nerve was
performed and intravesical pressure was measured manometrically. Urinary function
was evaluated by residual urine volume (RUV), International Prostatic Symptom
Score (IPSS), and quality of life (QoL). Sexual function was evaluated using the
International Index of Erectile Function (IIEF) scale and ejaculation function
classification.Compared with performing INS on the surfaces of prostate and
seminal vesicles in the R-group, INS on DF in the P-group exhibited higher
increasing intravesical pressure (7.3?±?1.5 vs 5.9?±?2.4?cmH2O, P = 0.008). In
addtion, the P-group exhibited lower RUV (34.3?±?27.2 vs 57.1?±?50.7?mL, P =
0.020), lower IPSS and QoL scores (7 days: 6.1?±?2.4 vs 9.5?±?5.9, P = 0.002 and
2.2?±?1.1 vs 2.9?±?1.1, P = 0.005; 1 month: 5.1?±?2.4 vs 6.6?±?2.2, P = 0.006 and
1.6?±?0.7 vs 2.1?±?0.6, P = 0.003, respectively), higher IIEF score (3 months:
10.7?±?2.1 vs 8.9?±?2.0, P = 0.000; 6 months: 14.8?±?2.2 vs 12.9?±?2.2, P =
0.001) and lower incidence of ejaculation dysfunction (3 months: 28.9% vs 52.8%,
P = 0.037; 6 months: 18.4% vs 44.4%, P = 0.016) postoperatively.Preservation of
DF during laparoscopic resection for selective male mid-low rectal cancer is
effective for protection of urogenital function.
|Adolescent
[MESH]
|Adult
[MESH]
|Aged
[MESH]
|Colectomy/*methods
[MESH]
|Fasciotomy/*methods
[MESH]
|Follow-Up Studies
[MESH]
|Humans
[MESH]
|Intraoperative Period
[MESH]
|Laparoscopy/*methods
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Postoperative Complications/*prevention & control
[MESH]
|Quality of Life
[MESH]
|Rectal Neoplasms/*surgery
[MESH]
|Retrospective Studies
[MESH]
|Sexual Dysfunction, Physiological/etiology/physiopathology/*prevention & control
[MESH]
|Sexuality
[MESH]
|Urination
[MESH]
|Urination Disorders/etiology/physiopathology/*prevention & control
[MESH]