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10.3892/ol.2016.4903

http://scihub22266oqcxt.onion/10.3892/ol.2016.4903
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C4998207!4998207!27602111
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suck abstract from ncbi


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pmid27602111      Oncol+Lett 2016 ; 12 (3): 1779-82
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  • HPV strain distribution in patients with genital warts in a female population sample #MMPMID27602111
  • Boda D; Neagu M; Constantin C; Voinescu RN; Caruntu C; Zurac S; Spandidos DA; Drakoulis N; Tsoukalas D; Tsatsakis AM
  • Oncol Lett 2016[Sep]; 12 (3): 1779-82 PMID27602111show ga
  • The incidence of human papillomavirus (HPV) in the human cancer domain is still a subject of intensive study. In this study, we examined cervical swab samples from 713 females with genital warts, and tested the samples for high- and low-risk genital HPV. HPV genotyping was assessed using a Genotyping test that detects HPV by the amplification of target DNA using polymerase chain reaction and nucleic acid hybridization. In total, we detected 37 anogenital HPV DNA genotypes [6, 11, 16, 18, 26, 31, 33, 35, 39, 40, 42, 45, 51, 52, 53, 54, 55, 56, 58, 59, 61, 62, 64, 66, 67, 68, 69, 70, 71, 72, 73 (MM9), 81, 82 (MM4), 83 (MM7), 84 (MM8), IS39 and CP6108] and investigated the incidence of these genotypes in the patients with genital warts. We found differences in the distribution of high-/low-risk strains and the incidence of high-risk strains was found to occur mainly in females under 35 years of age. The data from our study suggest that a detailed oral, rectal and genital identification of high-risk strains should be performed to visualize the entire pattern of possible triggers of carcinogenesis.
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