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2016 ; 12
(3
): 1818-1820
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Pulmonary infiltration with eosinophilia complicated with mucosa-associated
lymphoid tissue lymphoma: A case report
#MMPMID27588128
Liu Y
; Tangsun Y
; Xiao Y
; Zhang D
; Cao M
Oncol Lett
2016[Sep]; 12
(3
): 1818-1820
PMID27588128
show ga
Tissue eosinophilia is rarely observed in cases of non-Hodgkin's lymphoma of B
cell origin. The present study describes a rare case of mucosa-associated
lymphoid tissue (MALT) lymphoma, which was initially misdiagnosed as eosinophilic
pneumonia. The initial diagnosis was formed based on the results of chest
radiography, peripheral eosinophilia tests and bronchoalveolar lavage, and the
clinical course of the patient. Following administration of methylprednisolone
(40 mg/day) for 4 days and oral administration of prednisolone (30 mg/day), the
clinical course rapidly improved and the eosinophil count immediately decreased a
to normal level. However, abnormal shadows observed on computed tomography (CT)
scans of the chest did not diminish. At 6 months after the initiation of
treatment, CT-guided percutaneous lung biopsy was performed, and a final
diagnosis of primary pulmonary mucosa-associated lymphoid tissue lymphoma was
made based on immunohistochemical examination. Primary lung MALT lymphoma remains
a rare entity, with an indolent course and a reasonably favorable prognosis,
whose diagnosis may be challenging.