Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27557856
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Sci+Rep
2016 ; 6
(ä): 32151
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Exploration of pathological prediction of chronic kidney diseases by a novel
theory of bi-directional probability
#MMPMID27557856
Yang Y
; Luo M
; Xiao L
; Zhu XJ
; Wang C
; Fu X
; Yuan SG
; Xiao F
; Liu H
; Dong Z
; Liu FY
; Sun L
Sci Rep
2016[Aug]; 6
(ä): 32151
PMID27557856
show ga
In the clinic, the pathological types of chronic kidney diseases (CKD) are
considered references for choosing treatment protocols. From a statistical
viewpoint, a non-invasive method to predict pathological types of CKD is a focus
of our work. In the current study, following a frequency analysis of the clinical
indices of 588 CKD patients in the department of nephrology, a third-grade
class-A hospital, a novel theory is proposed: "bi-directional cumulative
probability dichotomy". Further, two models for the prediction and differential
diagnosis of CKD pathological type are established. The former indicates an
occurrence probability of the pathological types, and the latter indicates an
occurrence of CKD pathological type according to logistic binary regression. To
verify the models, data were collected from 135 patients, and the results showed
that the highest accuracy rate on membranous nephropathy (MN-100%), followed by
IgA nephropathy (IgAN-83.33%) and mild lesion type (MLN-73.53%), whereas lower
prediction accuracy was observed for mesangial proliferative glomerulonephritis
(0%) and focal segmental sclerosis type (21.74%). The models of bi-directional
probability prediction and differential diagnosis indicate a good prediction
value in MN, IgAN and MLN and may be considered alternative methods for the
pathological discrimination of CKD patients who are unable to undergo renal
biopsy.